C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: UPF1 regulator of nonsense transcripts homolog (yeast)
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000005007 UPF1 9606 + 19:18831938-18868236 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000262803 UPF1-001 18831938-18868236 protein_coding
  ENST00000594243 UPF1-009 18854913-18855680 retained_intron
  ENST00000594504 UPF1-003 18848133-18850776 processed_transcript
  ENST00000596842 UPF1-012 18859383-18868229 retained_intron
  ENST00000598209 UPF1-006 18849082-18852236 processed_transcript
  ENST00000598471 UPF1-008 18849813-18852194 processed_transcript
  ENST00000599848 UPF1-002 18832001-18868229 protein_coding
  ENST00000600012 UPF1-005 18849008-18852182 processed_transcript
  ENST00000600310 UPF1-007 18849166-18852254 processed_transcript
  ENST00000600689 UPF1-013 18862933-18868229 retained_intron
  ENST00000600868 UPF1-004 18849008-18852296 processed_transcript
  ENST00000601689 UPF1-010 18852998-18855157 retained_intron
  ENST00000601981 UPF1-011 18833130-18850691 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000262803ENST00000596842ENST00000599848ENST00000600689
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000262803 5.411±0.00 5.104±0.00 0.861±0.00 6.843±4.80 2.508±0.36 5.514±2.35 2.867±2.51 5.531±3.40 2.637±0.82 7.581±4.64 5.614±4.96 10.681±7.62 15.054±7.55 17.816±12.07
ENST00000596842 N/A N/A 0.643±0.00 N/A N/A N/A N/A N/A 0.984±0.00 N/A N/A N/A N/A N/A
ENST00000599848 5.499±0.00 N/A N/A 2.878±2.35 N/A N/A 0.984±0.55 N/A 1.668±0.00 2.806±1.77 2.968±0.00 6.294±2.10 4.403±0.00 5.791±0.00
ENST00000600689 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 10.657±0.00 N/A N/A

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000184 NAS:IEA nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
GO:0000785 IDA chromatin
GO:0000956 IMP nuclear-transcribed mRNA catabolic process
GO:0003677 IEA DNA binding
GO:0003682 IDA chromatin binding
GO:0003723 NAS RNA binding
GO:0004004 IDA ATP-dependent RNA helicase activity
GO:0004386 NAS:IEA helicase activity
GO:0005515 IPI protein binding
GO:0005524 IEA ATP binding
GO:0005634 IDA nucleus
GO:0005737 NAS:IEA cytoplasm
GO:0005829 TAS cytosol
GO:0006200 IDA ATP catabolic process
GO:0006260 IMP DNA replication
GO:0006281 IDA DNA repair
GO:0006406 TAS mRNA export from nucleus
GO:0006449 NAS regulation of translational termination
GO:0008270 IEA zinc ion binding
GO:0009048 IEA dosage compensation by inactivation of X chromosome
GO:0010467 TAS gene expression
GO:0016070 TAS RNA metabolic process
GO:0016071 TAS mRNA metabolic process
GO:0016787 IEA hydrolase activity
GO:0035145 IDA exon-exon junction complex
GO:0044530 IDA supraspliceosomal complex
GO:0044822 IDA poly(A) RNA binding
GO:0071044 IMP histone mRNA catabolic process

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000016302 upf1 upf1 regulator of nonsense transcripts homolog (yeast) protein_coding Danio_rerio
ENSMUSG00000058301 Upf1 UPF1 regulator of nonsense transcripts homolog (yeast) protein_coding Mus_musculus

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