C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: ATP-binding cassette, sub-family B (MDR/TAP), member 4
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000005471 ABCB4 9606 - 7:87401697-87480435 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000265723 ABCB4-002 87402049-87475739 protein_coding
  ENST00000358400 ABCB4-201 87402045-87475703 protein_coding
  ENST00000359206 ABCB4-001 87402045-87475659 protein_coding
  ENST00000417608 ABCB4-003 87462861-87480435 protein_coding
  ENST00000440025 ABCB4-008 87401697-87403201 protein_coding
  ENST00000453593 ABCB4-009 87402096-87475465 protein_coding
  ENST00000467079 ABCB4-006 87405920-87408234 retained_intron
  ENST00000467983 ABCB4-007 87402134-87403379 retained_intron
  ENST00000469770 ABCB4-005 87423575-87431500 retained_intron
  ENST00000473795 ABCB4-004 87452372-87475472 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000265723ENST00000358400ENST00000359206ENST00000417608ENST00000440025ENST00000453593ENST00000467079ENST00000467983ENST00000469770ENST00000473795
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000265723 N/A N/A N/A N/A N/A 0.170±0.00 N/A 4.272±0.00 4.988±0.00 N/A N/A N/A N/A 0.178±0.00
ENST00000358400 N/A 0.979±0.00 N/A N/A 0.269±0.00 N/A N/A N/A 2.903±0.00 N/A 0.256±0.00 0.108±0.00 0.349±0.21 0.030±0.00
ENST00000359206 N/A N/A N/A 0.062±0.00 N/A N/A 0.563±0.00 14.344±0.00 15.296±0.00 0.115±0.00 0.551±0.00 0.043±0.00 0.474±0.00 N/A
ENST00000417608 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.045±0.00
ENST00000440025 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.133±0.00 N/A N/A
ENST00000453593 0.276±0.00 N/A N/A 0.009±0.00 N/A 0.400±0.22 0.628±0.02 2.319±2.20 0.037±0.00 0.383±0.00 N/A 0.096±0.00 0.029±0.00 N/A
ENST00000467079 N/A 1.031±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.194±0.00 N/A
ENST00000467983 N/A N/A 1.758±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.575±0.00 N/A
ENST00000469770 N/A N/A 0.396±0.00 N/A N/A N/A N/A N/A 0.334±0.00 N/A N/A N/A N/A N/A
ENST00000473795 N/A N/A N/A N/A N/A 0.188±0.00 N/A N/A N/A N/A N/A 0.123±0.00 N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00052H CIL_00052H_0002 CGP 7:87345681-87480435

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005524 IEA ATP binding
GO:0005886 TAS plasma membrane
GO:0005887 TAS integral component of plasma membrane
GO:0006200 IEA ATP catabolic process
GO:0006629 TAS lipid metabolic process
GO:0006810 TAS:IEA transport
GO:0006855 IEA drug transmembrane transport
GO:0008559 IEA xenobiotic-transporting ATPase activity
GO:0016020 TAS membrane
GO:0016021 IBA:IEA integral component of membrane
GO:0016301 IEA kinase activity
GO:0016887 IEA ATPase activity
GO:0042493 TAS response to drug
GO:0042626 IBA:IEA ATPase activity, coupled to transmembrane movement of substances
GO:0042908 IEA xenobiotic transport
GO:0044255 TAS cellular lipid metabolic process
GO:0044281 TAS small molecule metabolic process
GO:0046581 IEA intercellular canaliculus
GO:0055085 IBA:IEA transmembrane transport
GO:0070062 IDA extracellular vesicular exosome

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000010936 abcb4 ATP-binding cassette, sub-family B (MDR/TAP), member 4 protein_coding Danio_rerio
ENSMUSG00000042476 Abcb4 ATP-binding cassette, sub-family B (MDR/TAP), member 4 protein_coding Mus_musculus

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