C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: chemokine (C-X3-C motif) ligand 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000006210 CX3CL1 9606 + 16:57372458-57385048 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000006053 CX3CL1-001 57372458-57385048 protein_coding
  ENST00000563383 CX3CL1-002 57372477-57385041 protein_coding
  ENST00000564948 CX3CL1-004 57372525-57382478 protein_coding
  ENST00000565912 CX3CL1-003 57376972-57385042 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000006053ENST00000563383ENST00000564948ENST00000565912
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000006053 28.439±0.00 13.808±0.00 2.712±0.00 17.926±8.15 20.204±17.71 4.009±3.79 5.042±4.04 8.567±7.58 2.632±0.77 133.925±130.31 7.964±6.41 5.039±2.89 5.559±5.21 12.686±11.63
ENST00000563383 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 5.872±0.00 N/A 0.379±0.00
ENST00000564948 N/A N/A N/A N/A N/A 0.332±0.00 N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000565912 N/A N/A N/A N/A N/A N/A N/A 0.055±0.00 0.491±0.00 N/A 0.587±0.00 N/A N/A 0.097±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0003ZH CIL_0003ZH_0001 CGP 16:57358772-57385048
CIL_0003ZE CIL_0003ZE_0001 CGP 16:57372458-57416062

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005102 TAS receptor binding
GO:0005515 IPI protein binding
GO:0005576 IEA:IDA extracellular region
GO:0005615 IEA extracellular space
GO:0005886 TAS plasma membrane
GO:0006935 IDA chemotaxis
GO:0006952 TAS defense response
GO:0006955 IEA:TAS immune response
GO:0007155 IEA cell adhesion
GO:0008009 TAS:IEA chemokine activity
GO:0009986 IDA cell surface
GO:0016020 IEA membrane
GO:0016021 IDA integral component of membrane
GO:0019221 TAS cytokine-mediated signaling pathway
GO:0030593 IEA neutrophil chemotaxis
GO:0030595 TAS leukocyte chemotaxis
GO:0032914 IEA positive regulation of transforming growth factor beta1 production
GO:0042060 IEA wound healing
GO:0045766 IEA positive regulation of angiogenesis
GO:0048246 IEA macrophage chemotaxis
GO:0048247 IEA lymphocyte chemotaxis
GO:0050729 IEP positive regulation of inflammatory response
GO:0050902 TAS leukocyte adhesive activation
GO:0051041 IDA positive regulation of calcium-independent cell-cell adhesion
GO:0060055 IEA angiogenesis involved in wound healing
GO:0060326 IEA cell chemotaxis
GO:2001240 IEA negative regulation of extrinsic apoptotic signaling pathway in absence of ligand

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSMUSG00000031778 Cx3cl1 chemokine (C-X3-C motif) ligand 1 protein_coding Mus_musculus

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