C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: lysine (K)-specific demethylase 7A
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000006459 KDM7A 9606 - 7:140084746-140177035 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000397560 KDM7A-001 140084746-140177035 protein_coding
  ENST00000472616 KDM7A-002 140084855-140119142 nonsense_mediated_decay
  ENST00000478996 KDM7A-003 140090903-140092141 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000397560ENST00000472616
Transcript ID Adipose Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000397560 3.628±0.00 1.760±0.00 1.302±0.49 3.628±2.32 3.224±1.37 1.718±0.14 0.752±0.20 1.621±0.99 3.089±1.77 3.819±2.56 1.705±1.46 1.205±0.15 5.658±2.86
ENST00000472616 1.195±0.00 N/A 0.550±0.00 0.740±0.00 0.576±0.00 N/A 0.665±0.00 0.369±0.00 2.420±0.00 4.837±0.00 0.848±0.70 0.953±0.55 0.923±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008ZU CIL_0008ZU_0001 VISTA 7:139910788-140514447
CIL_00030A CIL_00030A_0001 CGP 7:140023744-140177035
CIL_000307 CIL_000307_0001 CGP 7:140084746-140404433

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005506 IDA iron ion binding
GO:0005515 IEA protein binding
GO:0005634 IDA nucleus
GO:0005730 IDA nucleolus
GO:0006351 IEA transcription, DNA-templated
GO:0008270 IDA:IEA zinc ion binding
GO:0016706 IDA oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors
GO:0030901 ISS midbrain development
GO:0032454 IDA histone demethylase activity (H3-K9 specific)
GO:0033169 IDA histone H3-K9 demethylation
GO:0035064 IDA methylated histone binding
GO:0035574 IDA histone H4-K20 demethylation
GO:0035575 IDA histone demethylase activity (H4-K20 specific)
GO:0045893 IEA positive regulation of transcription, DNA-templated
GO:0051864 IDA histone demethylase activity (H3-K36 specific)
GO:0055114 IEA oxidation-reduction process
GO:0070544 IDA histone H3-K36 demethylation
GO:0071557 IDA histone H3-K27 demethylation
GO:0071558 IDA histone demethylase activity (H3-K27 specific)

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000018111 kdm7aa lysine (K)-specific demethylase 7Aa protein_coding Danio_rerio
ENSDARG00000018559 kdm7ab lysine (K)-specific demethylase 7Ab protein_coding Danio_rerio
ENSMUSG00000042599 Kdm7a lysine (K)-specific demethylase 7A protein_coding Mus_musculus

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