C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: FERM, RhoGEF and pleckstrin domain protein 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000006607 FARP2 9606 + 2:241356243-241494841 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000264042 FARP2-001 241356243-241494841 protein_coding
  ENST00000373287 FARP2-002 241356297-241466030 protein_coding
  ENST00000412332 FARP2-022 241493393-241494840 protein_coding
  ENST00000413432 FARP2-014 241434230-241447149 protein_coding
  ENST00000418082 FARP2-007 241372678-241407608 protein_coding
  ENST00000422951 FARP2-017 241463336-241466036 protein_coding
  ENST00000444371 FARP2-021 241489961-241494119 protein_coding
  ENST00000445489 FARP2-008 241372849-241403923 protein_coding
  ENST00000464142 FARP2-009 241373082-241403902 processed_transcript
  ENST00000467260 FARP2-011 241386743-241405403 processed_transcript
  ENST00000470617 FARP2-003 241488148-241494840 retained_intron
  ENST00000471447 FARP2-012 241410941-241432241 retained_intron
  ENST00000473082 FARP2-010 241373189-241405402 processed_transcript
  ENST00000473510 FARP2-016 241462532-241463525 retained_intron
  ENST00000476799 FARP2-015 241456435-241463458 retained_intron
  ENST00000478489 FARP2-004 241356295-241405403 processed_transcript
  ENST00000479427 FARP2-005 241356299-241395984 processed_transcript
  ENST00000485051 FARP2-013 241410945-241434187 retained_intron
  ENST00000486736 FARP2-020 241484090-241491649 retained_intron
  ENST00000491425 FARP2-019 241471312-241488510 processed_transcript
  ENST00000492868 FARP2-006 241372560-241395644 processed_transcript
  ENST00000496470 FARP2-018 241463580-241468320 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdrenalBreastColonKidneyLiverLungOvaryPlacentaTestisENST00000264042ENST00000373287ENST00000413432
Transcript ID Adrenal Breast Colon Kidney Liver Lung Ovary Placenta Testis
ENST00000264042 N/A N/A N/A N/A N/A N/A N/A N/A 10.079±0.00
ENST00000373287 N/A N/A N/A N/A N/A 4.994±0.00 N/A N/A 16.423±0.00
ENST00000413432 4.236±0.00 2.151±0.00 3.056±0.00 2.448±0.00 1.091±0.00 3.029±0.00 5.102±0.92 2.644±0.58 8.559±1.58

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0002JL CIL_0002JL_0001 CGP 2:241315100-241494841
CIL_0004UB CIL_0004UB_0002 CGP 2:241356243-241509730

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005089 IDA:IEA Rho guanyl-nucleotide exchange factor activity
GO:0005737 IDA cytoplasm
GO:0005829 TAS cytosol
GO:0005856 IEA cytoskeleton
GO:0007155 ISS cell adhesion
GO:0007411 TAS axon guidance
GO:0008092 IEA cytoskeletal protein binding
GO:0016322 IDA neuron remodeling
GO:0016601 IDA Rac protein signal transduction
GO:0019898 IEA extrinsic component of membrane
GO:0030316 ISS osteoclast differentiation
GO:0030676 ISS Rac guanyl-nucleotide exchange factor activity
GO:0031532 ISS actin cytoskeleton reorganization
GO:0032321 IDA positive regulation of Rho GTPase activity
GO:0032855 ISS positive regulation of Rac GTPase activity
GO:0033623 ISS regulation of integrin activation
GO:0035023 IEA regulation of Rho protein signal transduction
GO:0071526 ISS semaphorin-plexin signaling pathway
GO:0071800 ISS podosome assembly

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000016429 farp2 FERM, RhoGEF and pleckstrin domain protein 2 protein_coding Danio_rerio
ENSMUSG00000034066 Farp2 FERM, RhoGEF and pleckstrin domain protein 2 protein_coding Mus_musculus

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