C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: FERM, RhoGEF and pleckstrin domain protein 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000034066 Farp2 10090 + 1:93512079-93621976 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000120301 Farp2-001 93512079-93621976 protein_coding
  ENSMUST00000122402 Farp2-002 93512112-93581296 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; KidneyLiverPlacentaENSMUST00000120301
Transcript ID Kidney Liver Placenta
ENSMUST00000120301 5.347±0.00 4.475±0.77 11.292±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0002JL CIL_0002JL_0002 CGP 1:93478964-93621976
CIL_0004UB CIL_0004UB_0003 CGP 1:93512079-93658659

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005089 ISO Rho guanyl-nucleotide exchange factor activity
GO:0005737 ISO cytoplasm
GO:0005829 TAS cytosol
GO:0005856 IEA cytoskeleton
GO:0007155 IMP cell adhesion
GO:0008092 IEA cytoskeletal protein binding
GO:0016322 ISO neuron remodeling
GO:0016601 ISO Rac protein signal transduction
GO:0019898 IEA extrinsic component of membrane
GO:0030316 IMP osteoclast differentiation
GO:0030676 IDA Rac guanyl-nucleotide exchange factor activity
GO:0031532 IMP actin cytoskeleton reorganization
GO:0032321 ISO positive regulation of Rho GTPase activity
GO:0032855 IDA positive regulation of Rac GTPase activity
GO:0033623 IMP regulation of integrin activation
GO:0071526 IMP semaphorin-plexin signaling pathway
GO:0071800 IMP podosome assembly

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000016429 farp2 FERM, RhoGEF and pleckstrin domain protein 2 protein_coding Danio_rerio
ENSG00000006607 FARP2 FERM, RhoGEF and pleckstrin domain protein 2 protein_coding Homo_sapiens

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