C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: selectin E
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000007908 SELE 9606 - 1:169722641-169764705 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000333360 SELE-001 169722641-169734062 protein_coding
  ENST00000367774 SELE-004 169725729-169733660 protein_coding
  ENST00000367775 SELE-003 169722641-169733659 protein_coding
  ENST00000367776 SELE-005 169722641-169733660 protein_coding
  ENST00000367777 SELE-002 169722641-169733660 protein_coding
  ENST00000461085 SELE-006 169731491-169732718 retained_intron
  ENST00000609271 SELE-007 169733577-169764705 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000333360ENST00000367774ENST00000367775ENST00000367776ENST00000367777
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000333360 N/A 2.803±0.00 0.206±0.00 0.530±0.00 0.719±0.22 0.367±0.00 0.131±0.00 0.118±0.00 3.125±0.00 9.477±0.00 0.293±0.00 2.388±0.58 0.416±0.11 3.821±0.00
ENST00000367774 N/A N/A 0.205±0.00 N/A N/A N/A 0.079±0.00 N/A N/A N/A N/A N/A 0.293±0.00 N/A
ENST00000367775 N/A N/A N/A N/A 0.721±0.00 0.324±0.28 N/A 0.547±0.00 2.498±0.00 N/A 0.237±0.00 0.889±0.08 N/A N/A
ENST00000367776 0.120±0.00 N/A N/A 0.371±0.00 0.267±0.05 N/A N/A N/A N/A 0.051±0.00 N/A 0.196±0.00 0.628±0.00 0.441±0.00
ENST00000367777 0.144±0.00 N/A N/A N/A N/A N/A 0.052±0.00 N/A N/A N/A N/A 0.872±0.00 N/A 0.895±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00093H CIL_00093H_0001 VISTA 1:169641255-170243938

Gene Ontology
GO IDEvidence TypeGO Description
GO:0002092 IDA positive regulation of receptor internalization
GO:0002523 TAS leukocyte migration involved in inflammatory response
GO:0002687 IEA positive regulation of leukocyte migration
GO:0004888 IMP transmembrane signaling receptor activity
GO:0005515 IPI:IEA protein binding
GO:0005615 IDA extracellular space
GO:0005886 TAS plasma membrane
GO:0005901 IDA caveola
GO:0005905 IDA coated pit
GO:0006954 TAS inflammatory response
GO:0007155 IEA cell adhesion
GO:0007157 IMP heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules
GO:0007159 IDA leukocyte cell-cell adhesion
GO:0007202 IMP activation of phospholipase C activity
GO:0007596 TAS blood coagulation
GO:0016020 IEA membrane
GO:0016021 IEA integral component of membrane
GO:0019722 TAS calcium-mediated signaling
GO:0030029 IDA actin filament-based process
GO:0030246 IEA carbohydrate binding
GO:0030863 IDA cortical cytoskeleton
GO:0032496 TAS response to lipopolysaccharide
GO:0033691 IDA sialic acid binding
GO:0034612 TAS response to tumor necrosis factor
GO:0043274 IDA phospholipase binding
GO:0045121 IDA membrane raft
GO:0048471 IDA perinuclear region of cytoplasm
GO:0050727 TAS regulation of inflammatory response
GO:0050900 TAS leukocyte migration
GO:0050901 IMP leukocyte tethering or rolling
GO:0070492 IDA oligosaccharide binding
GO:0070555 IDA response to interleukin-1

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000009123 sele selectin E protein_coding Danio_rerio
ENSDARG00000042138 selp selectin P protein_coding Danio_rerio
ENSMUSG00000026582 Sele selectin, endothelial cell protein_coding Mus_musculus

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