C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: cryptochrome circadian clock 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000008405 CRY1 9606 - 12:106991364-107093829 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000008527 CRY1-001 106991364-107093829 protein_coding
  ENST00000546722 CRY1-005 106999789-107001851 retained_intron
  ENST00000549356 CRY1-004 106992487-106997539 protein_coding
  ENST00000550633 CRY1-003 107072935-107093513 processed_transcript
  ENST00000552790 CRY1-002 106991367-107050359 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000008527ENST00000549356ENST00000552790
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000008527 4.565±0.00 3.550±0.00 2.049±0.00 3.963±2.00 4.134±0.19 2.364±1.48 1.994±1.05 4.220±3.09 2.379±0.89 4.114±2.55 1.286±0.80 5.510±3.19 4.620±1.11 30.288±14.84
ENST00000549356 N/A N/A N/A N/A N/A 2.990±0.00 N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000552790 N/A N/A 0.317±0.00 N/A 0.583±0.00 N/A N/A N/A N/A N/A N/A 0.495±0.00 N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0001MD CIL_0001MD_0001 CGP 12:106977291-107093829

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000122 IDA negative regulation of transcription from RNA polymerase II promoter
GO:0000166 IEA nucleotide binding
GO:0000989 IDA transcription factor binding transcription factor activity
GO:0001046 IEA core promoter sequence-specific DNA binding
GO:0001047 ISS core promoter binding
GO:0003677 TAS DNA binding
GO:0003690 IDA double-stranded DNA binding
GO:0003913 IEA DNA photolyase activity
GO:0005515 IPI protein binding
GO:0005634 ISS nucleus
GO:0005730 IDA nucleolus
GO:0005737 IDA cytoplasm
GO:0005739 IEA mitochondrion
GO:0006094 ISS gluconeogenesis
GO:0006281 IEA DNA repair
GO:0006351 IEA transcription, DNA-templated
GO:0006975 ISS DNA damage induced protein phosphorylation
GO:0007623 IEA circadian rhythm
GO:0008134 IEA transcription factor binding
GO:0009785 NAS blue light signaling pathway
GO:0009882 NAS blue light photoreceptor activity
GO:0018298 IEA protein-chromophore linkage
GO:0019900 IEA kinase binding
GO:0019901 IEA protein kinase binding
GO:0019902 IPI phosphatase binding
GO:0019915 IEA lipid storage
GO:0031397 ISS negative regulation of protein ubiquitination
GO:0032868 IEA response to insulin
GO:0032922 ISS circadian regulation of gene expression
GO:0033762 ISS response to glucagon
GO:0035257 IPI nuclear hormone receptor binding
GO:0042593 ISS glucose homeostasis
GO:0042752 ISS regulation of circadian rhythm
GO:0042754 ISS negative regulation of circadian rhythm
GO:0042826 IEA histone deacetylase binding
GO:0043130 ISS ubiquitin binding
GO:0043153 ISS entrainment of circadian clock by photoperiod
GO:0045744 ISS negative regulation of G-protein coupled receptor protein signaling pathway
GO:0045892 ISS negative regulation of transcription, DNA-templated
GO:2000001 ISS regulation of DNA damage checkpoint
GO:2000323 ISS negative regulation of glucocorticoid receptor signaling pathway
GO:2000850 IEA negative regulation of glucocorticoid secretion

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000011583 cry1b cryptochrome 1b protein_coding Danio_rerio
ENSDARG00000045768 cry1a cryptochrome 1a protein_coding Danio_rerio
ENSMUSG00000020038 Cry1 cryptochrome 1 (photolyase-like) protein_coding Mus_musculus

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