C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: leucyl-tRNA synthetase 2, mitochondrial
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000011376 LARS2 9606 + 3:45388506-45549421 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000265537 LARS2-001 45388506-45548837 protein_coding
  ENST00000414984 LARS2-003 45388564-45547609 protein_coding
  ENST00000415258 LARS2-002 45388561-45549421 protein_coding
  ENST00000430399 LARS2-005 45388619-45400353 protein_coding
  ENST00000431023 LARS2-006 45388564-45446935 protein_coding
  ENST00000467936 LARS2-008 45500541-45538463 processed_transcript
  ENST00000474585 LARS2-009 45541594-45547554 processed_transcript
  ENST00000485461 LARS2-007 45517963-45547404 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000265537ENST00000415258ENST00000467936
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000265537 1.851±0.00 2.217±0.00 1.003±0.00 3.407±0.93 1.745±0.70 2.161±0.08 2.220±1.58 3.636±2.86 1.753±0.87 1.764±0.07 0.981±0.18 2.567±1.34 3.911±1.20 2.326±0.43
ENST00000415258 0.204±0.00 N/A 0.464±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.543±0.00 0.462±0.00
ENST00000467936 N/A N/A 1.539±0.00 N/A N/A N/A N/A N/A N/A N/A N/A 3.024±0.00 1.758±0.00 2.944±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00073N CIL_00073N_0001 CGP 3:45224466-45549421
CIL_00073L CIL_00073L_0001 CGP 3:45388506-45686338

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000166 IEA nucleotide binding
GO:0002161 IEA aminoacyl-tRNA editing activity
GO:0004812 IEA aminoacyl-tRNA ligase activity
GO:0004823 IEA leucine-tRNA ligase activity
GO:0005524 IEA ATP binding
GO:0005739 IEA mitochondrion
GO:0005759 TAS mitochondrial matrix
GO:0006418 TAS:IEA tRNA aminoacylation for protein translation
GO:0006429 IEA leucyl-tRNA aminoacylation
GO:0006450 IEA regulation of translational fidelity
GO:0010467 TAS gene expression

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000075337 lars2 leucyl-tRNA synthetase 2, mitochondrial protein_coding Danio_rerio
ENSDARG00000089393 LARS2 (2 of 2) leucyl-tRNA synthetase 2, mitochondrial protein_coding Danio_rerio
ENSMUSG00000035202 Lars2 leucyl-tRNA synthetase, mitochondrial protein_coding Mus_musculus

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