C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: mitogen-activated protein kinase kinase kinase kinase 5
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000012983 MAP4K5 9606 - 14:50418501-50561126 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000013125 MAP4K5-001 50418525-50532609 protein_coding
  ENST00000554066 MAP4K5-003 50485929-50505128 retained_intron
  ENST00000554091 MAP4K5-011 50464078-50532087 nonsense_mediated_decay
  ENST00000554273 MAP4K5-004 50504799-50532655 protein_coding
  ENST00000554990 MAP4K5-002 50418501-50450600 retained_intron
  ENST00000555216 MAP4K5-008 50475092-50561126 protein_coding
  ENST00000557124 MAP4K5-007 50434964-50438401 retained_intron
  ENST00000557210 MAP4K5-005 50462693-50483149 retained_intron
  ENST00000557390 MAP4K5-006 50476274-50532472 protein_coding
  ENST00000557578 MAP4K5-010 50468690-50486145 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungOvaryPlacentaTestisENST00000013125ENST00000554990
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Ovary Placenta Testis
ENST00000013125 3.330±0.00 2.644±0.00 1.466±0.00 8.405±0.96 5.325±0.45 5.173±0.61 2.582±0.00 6.676±0.00 N/A 5.995±2.37 7.471±2.16 4.124±1.15 6.549±0.00
ENST00000554990 N/A N/A 0.829±0.00 N/A 1.898±0.00 N/A 0.591±0.00 N/A 3.359±0.00 N/A N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0005HO CIL_0005HO_0002 CGP 14:50329592-50561126
CIL_0005HD CIL_0005HD_0002 CGP 14:50418501-50633068

Gene Ontology

GO IDEvidence TypeGO Description
GO:0004672 IEA protein kinase activity
GO:0004713 IEA protein tyrosine kinase activity
GO:0005083 IEA small GTPase regulator activity
GO:0005524 IEA ATP binding
GO:0006468 IEA protein phosphorylation
GO:0016772 IEA transferase activity, transferring phosphorus-containing groups

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000039125 map4k5 mitogen-activated protein kinase kinase kinase kinase 5 protein_coding Danio_rerio
ENSMUSG00000034761 Map4k5 mitogen-activated protein kinase kinase kinase kinase 5 protein_coding Mus_musculus

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