C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: mitogen-activated protein kinase kinase kinase kinase 5
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000034761 Map4k5 10090 - 12:69803750-69893200 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000049239 Map4k5-201 69803759-69893163 protein_coding
  ENSMUST00000110567 Map4k5-003 69803750-69893009 protein_coding
  ENSMUST00000110570 Map4k5-001 69803750-69893200 protein_coding
  ENSMUST00000124715 Map4k5-005 69844874-69874334 retained_intron
  ENSMUST00000126584 Map4k5-006 69803761-69818453 retained_intron
  ENSMUST00000133688 Map4k5-004 69848567-69893123 retained_intron
  ENSMUST00000147451 Map4k5-007 69849037-69856424 retained_intron
  ENSMUST00000153550 Map4k5-008 69817782-69818857 processed_transcript
  ENSMUST00000153712 Map4k5-002 69803750-69893103 processed_transcript
  ENSMUST00000171211 Map4k5-202 69803759-69893103 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000049239ENSMUST00000110567ENSMUST00000110570ENSMUST00000126584ENSMUST00000133688ENSMUST00000153712
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000049239 N/A N/A N/A 5.414±0.00 2.317±0.36 3.005±0.57 N/A N/A 1.064±0.34 N/A 2.028±0.37 5.255±1.90 6.840±0.30 2.018±0.00
ENSMUST00000110567 N/A N/A N/A N/A 1.485±0.00 N/A N/A N/A N/A N/A N/A 3.304±0.00 N/A N/A
ENSMUST00000110570 5.496±2.65 N/A 10.610±2.34 7.827±0.37 2.267±0.71 2.687±0.00 3.067±0.41 4.689±0.09 6.382±5.89 4.823±0.71 5.712±1.31 4.983±0.40 8.400±3.08 4.660±0.47
ENSMUST00000126584 2.037±1.43 N/A 2.598±0.14 N/A 1.131±0.10 N/A N/A N/A 2.010±0.85 1.686±0.09 N/A N/A N/A N/A
ENSMUST00000133688 N/A 9.336±2.62 N/A N/A 9.624±2.92 8.770±2.32 N/A N/A N/A 2.920±0.00 N/A 15.787±4.61 N/A N/A
ENSMUST00000153712 N/A N/A N/A N/A N/A N/A N/A N/A N/A 3.662±0.00 N/A 7.479±0.00 N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0005HO CIL_0005HO_0003 CGP 12:69746848-69893200
CIL_0005HD CIL_0005HD_0003 CGP 12:69803750-69964085

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004674 IEA protein serine/threonine kinase activity
GO:0005083 IEA small GTPase regulator activity
GO:0005524 IEA ATP binding
GO:0005737 ISS cytoplasm
GO:0006468 IEA protein phosphorylation
GO:0035556 ISS intracellular signal transduction
GO:0050790 IEA regulation of catalytic activity

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000039125 map4k5 mitogen-activated protein kinase kinase kinase kinase 5 protein_coding Danio_rerio
ENSG00000012983 MAP4K5 mitogen-activated protein kinase kinase kinase kinase 5 protein_coding Homo_sapiens

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