C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: BH3 interacting domain death agonist
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000015475 BID 9606 - 22:17734138-17774770 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000317361 BID-002 17734138-17774016 protein_coding
  ENST00000342111 BID-003 17735499-17774412 protein_coding
  ENST00000399765 BID-004 17734175-17774489 protein_coding
  ENST00000399767 BID-201 17734142-17774495 protein_coding
  ENST00000399774 BID-001 17734171-17774492 protein_coding
  ENST00000473439 BID-006 17738058-17774495 processed_transcript
  ENST00000494097 BID-005 17735222-17741194 retained_intron
  ENST00000550946 BID-011 17735552-17774412 retained_intron
  ENST00000551952 BID-009 17735552-17774665 protein_coding
  ENST00000552886 BID-008 17739448-17774770 processed_transcript
  ENST00000611040 BID-202 17735552-17774665 protein_coding
  ENST00000614949 BID-203 17734142-17774495 protein_coding
  ENST00000615414 BID-204 17734142-17774042 protein_coding
  ENST00000617586 BID-205 17740031-17774495 protein_coding
  ENST00000622694 BID-206 17734142-17774495 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBreastColonKidneyLiverLungOvaryPlacentaTestisENST00000342111ENST00000399765ENST00000399774ENST00000473439ENST00000494097ENST00000551952ENST00000614949ENST00000622694
Transcript ID Adipose Adrenal Bladder Breast Colon Kidney Liver Lung Ovary Placenta Testis
ENST00000342111 N/A N/A N/A N/A N/A N/A 7.867±0.00 14.764±0.00 20.704±0.00 N/A N/A
ENST00000399765 1.239±0.00 2.385±0.00 0.050±0.00 N/A N/A N/A 1.970±0.00 1.803±1.41 2.358±0.00 N/A N/A
ENST00000399774 N/A 3.085±0.00 N/A N/A N/A N/A 1.687±0.94 N/A 8.034±0.00 2.765±0.00 1.056±0.00
ENST00000473439 7.524±0.00 N/A N/A N/A N/A 2.466±0.00 N/A N/A N/A N/A N/A
ENST00000494097 N/A N/A 0.041±0.00 N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000551952 N/A N/A N/A N/A N/A N/A N/A N/A 24.943±0.00 8.918±0.00 N/A
ENST00000614949 N/A N/A N/A N/A 2.096±0.00 N/A N/A N/A N/A N/A N/A
ENST00000622694 1.920±0.00 2.620±0.00 N/A 2.238±0.00 N/A 3.361±0.00 N/A N/A 3.699±0.00 2.867±0.58 N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_000242 CIL_000242_0001 CGP 22:17628855-17774770
CIL_0002Z7 CIL_0002Z7_0001 CGP 22:17734138-18024559

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001836 IDA release of cytochrome c from mitochondria
GO:0005123 TAS death receptor binding
GO:0005515 IPI protein binding
GO:0005737 IEA cytoplasm
GO:0005739 TAS mitochondrion
GO:0005741 TAS mitochondrial outer membrane
GO:0005829 TAS cytosol
GO:0006626 IEA protein targeting to mitochondrion
GO:0006915 TAS apoptotic process
GO:0006919 IEA activation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0007420 IEA brain development
GO:0008625 TAS extrinsic apoptotic signaling pathway via death domain receptors
GO:0008637 TAS apoptotic mitochondrial changes
GO:0016020 TAS membrane
GO:0031625 IEA ubiquitin protein ligase binding
GO:0032355 IEA response to estradiol
GO:0032459 IEA regulation of protein oligomerization
GO:0032461 IDA positive regulation of protein oligomerization
GO:0032464 IDA positive regulation of protein homooligomerization
GO:0032592 IEA integral component of mitochondrial membrane
GO:0034349 IEA glial cell apoptotic process
GO:0042127 IEA regulation of cell proliferation
GO:0042770 TAS signal transduction in response to DNA damage
GO:0043065 IMP:IEA positive regulation of apoptotic process
GO:0051260 IEA protein homooligomerization
GO:0051402 TAS neuron apoptotic process
GO:0070062 IDA extracellular vesicular exosome
GO:0090150 IDA establishment of protein localization to membrane
GO:0090200 IMP positive regulation of release of cytochrome c from mitochondria
GO:0097191 IEA extrinsic apoptotic signaling pathway
GO:0097193 TAS intrinsic apoptotic signaling pathway
GO:0097284 IEA hepatocyte apoptotic process
GO:0097345 IEA mitochondrial outer membrane permeabilization
GO:1900740 TAS positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway
GO:1901030 TAS positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway
GO:1902108 IEA regulation of mitochondrial membrane permeability involved in apoptotic process
GO:2000045 IEA regulation of G1/S transition of mitotic cell cycle
GO:2001238 IMP positive regulation of extrinsic apoptotic signaling pathway
GO:2001244 TAS positive regulation of intrinsic apoptotic signaling pathway

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSMUSG00000004446 Bid BH3 interacting domain death agonist protein_coding Mus_musculus

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