C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: runt-related transcription factor 3
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000020633 RUNX3 9606 - 1:24899511-24965121 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000308873 RUNX3-001 24899518-24929877 protein_coding
  ENST00000338888 RUNX3-002 24901029-24964984 protein_coding
  ENST00000399916 RUNX3-201 24899511-24965010 protein_coding
  ENST00000479341 RUNX3-003 24929737-24965121 processed_transcript
  ENST00000496967 RUNX3-004 24902572-24928798 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungOvaryPlacentaTestisENST00000308873ENST00000338888ENST00000399916ENST00000496967
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Ovary Placenta Testis
ENST00000308873 0.875±0.00 11.102±0.00 N/A 0.214±0.20 1.419±0.00 0.721±0.00 0.221±0.16 0.430±0.08 0.316±0.00 10.787±0.00 3.163±2.70 0.838±0.13 0.845±0.00
ENST00000338888 N/A N/A N/A 0.064±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000399916 N/A N/A N/A N/A 0.177±0.00 0.598±0.00 N/A N/A 0.326±0.00 N/A N/A N/A N/A
ENST00000496967 N/A N/A 0.117±0.00 N/A 1.203±0.00 N/A N/A N/A N/A N/A N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0007ZX CIL_0007ZX_0001 VISTA 1:24547215-25148615

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000122 ISS negative regulation of transcription from RNA polymerase II promoter
GO:0000790 ISS nuclear chromatin
GO:0000977 ISS RNA polymerase II regulatory region sequence-specific DNA binding
GO:0000981 ISS sequence-specific DNA binding RNA polymerase II transcription factor activity
GO:0002062 IEA chondrocyte differentiation
GO:0003677 IEA DNA binding
GO:0003700 TAS:IEA sequence-specific DNA binding transcription factor activity
GO:0005515 IPI protein binding
GO:0005524 NAS ATP binding
GO:0005634 IDA nucleus
GO:0005737 IDA cytoplasm
GO:0006355 NAS:IEA regulation of transcription, DNA-templated
GO:0006366 TAS transcription from RNA polymerase II promoter
GO:0006468 IDA protein phosphorylation
GO:0007411 IEA axon guidance
GO:0031069 IEA hair follicle morphogenesis
GO:0031175 IEA neuron projection development
GO:0032609 IEA interferon-gamma production
GO:0045786 ISS negative regulation of cell cycle
GO:0048469 IEA cell maturation
GO:0048935 TAS peripheral nervous system neuron development
GO:0050680 ISS negative regulation of epithelial cell proliferation
GO:2001238 IEA positive regulation of extrinsic apoptotic signaling pathway

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000052826 runx3 runt-related transcription factor 3 protein_coding Danio_rerio
ENSMUSG00000070691 Runx3 runt related transcription factor 3 protein_coding Mus_musculus

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