C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: runt-related transcription factor 3
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000308873 RUNX3-001 ENSG00000020633 9606 - 1:24899518-24929877 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBrainBreastColonHeartKidneyLiverLungOvaryPlacentaTestisENST00000308873
Transcript ID Adipose Adrenal Brain Breast Colon Heart Kidney Liver Lung Ovary Placenta Testis
ENST00000308873 0.875±0.00 11.102±0.00 0.214±0.20 1.419±0.00 0.721±0.00 0.221±0.16 0.430±0.08 0.316±0.00 10.787±0.00 3.163±2.70 0.838±0.13 0.845±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0007ZX CIL_0007ZX_0001 VISTA 1:24547215-25148615

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000122 ISS negative regulation of transcription from RNA polymerase II promoter
GO:0000790 ISS nuclear chromatin
GO:0000977 ISS RNA polymerase II regulatory region sequence-specific DNA binding
GO:0000981 ISS sequence-specific DNA binding RNA polymerase II transcription factor activity
GO:0003677 IEA DNA binding
GO:0003700 TAS:IEA sequence-specific DNA binding transcription factor activity
GO:0005515 IPI protein binding
GO:0005524 NAS ATP binding
GO:0005634 IDA nucleus
GO:0005737 IDA cytoplasm
GO:0006355 NAS:IEA regulation of transcription, DNA-templated
GO:0006366 TAS transcription from RNA polymerase II promoter
GO:0006468 IDA protein phosphorylation
GO:0045786 ISS negative regulation of cell cycle
GO:0048935 TAS peripheral nervous system neuron development
GO:0050680 ISS negative regulation of epithelial cell proliferation

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000119564 Runx3-002 protein_coding Mus_musculus 0 1507
ENSMUST00000056977 Runx3-001 protein_coding Mus_musculus 0 1482
ENSMUST00000156478 Runx3-003 retained_intron Mus_musculus 0 412
ENSMUST00000168195 Runx1-004 protein_coding Mus_musculus 0 342
ENSMUST00000023673 Runx1-001 protein_coding Mus_musculus 0 342
ENSMUST00000113956 Runx1-003 protein_coding Mus_musculus 0 316
ENSMUST00000189126 Runx1-005 retained_intron Mus_musculus 0 259

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