C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: runt related transcription factor 3
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000070691 Runx3 10090 + 4:135120652-135177990 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000056977 Runx3-001 135120652-135177990 protein_coding
  ENSMUST00000119564 Runx3-002 135152496-135176181 protein_coding
  ENSMUST00000127109 Runx3-006 135154436-135155342 processed_transcript
  ENSMUST00000137027 Runx3-004 135153160-135155371 processed_transcript
  ENSMUST00000140642 Runx3-005 135153505-135155426 processed_transcript
  ENSMUST00000156478 Runx3-003 135152938-135155609 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000056977ENSMUST00000119564ENSMUST00000156478
Transcript ID Adipose Adrenal Bladder Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000056977 0.201±0.12 0.655±0.19 0.025±0.00 2.044±1.61 0.684±0.11 0.039±0.02 0.363±0.19 0.132±0.12 0.648±0.30 0.039±0.02 0.309±0.09 0.065±0.04 0.241±0.07
ENSMUST00000119564 0.051±0.00 0.288±0.16 N/A 1.992±1.13 0.128±0.02 N/A N/A 0.445±0.36 0.228±0.02 N/A 0.130±0.00 0.151±0.02 0.554±0.10
ENSMUST00000156478 N/A N/A N/A N/A N/A N/A N/A 0.138±0.00 N/A N/A N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0007ZX CIL_0007ZX_0002 VISTA 4:134905845-135507207

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000122 IDA negative regulation of transcription from RNA polymerase II promoter
GO:0000790 IDA nuclear chromatin
GO:0000977 IDA RNA polymerase II regulatory region sequence-specific DNA binding
GO:0000981 IDA sequence-specific DNA binding RNA polymerase II transcription factor activity
GO:0002062 IGI chondrocyte differentiation
GO:0003677 IDA DNA binding
GO:0003700 IEA sequence-specific DNA binding transcription factor activity
GO:0005515 IPI protein binding
GO:0005524 IEA ATP binding
GO:0005634 IDA nucleus
GO:0005737 IEA cytoplasm
GO:0006355 IEA regulation of transcription, DNA-templated
GO:0006468 IEA protein phosphorylation
GO:0007411 IMP axon guidance
GO:0031069 IMP hair follicle morphogenesis
GO:0031175 IMP neuron projection development
GO:0032609 IDA interferon-gamma production
GO:0042789 IDA mRNA transcription from RNA polymerase II promoter
GO:0045786 IMP negative regulation of cell cycle
GO:0048469 IGI cell maturation
GO:0050680 IMP negative regulation of epithelial cell proliferation
GO:2001238 IMP positive regulation of extrinsic apoptotic signaling pathway

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000052826 runx3 runt-related transcription factor 3 protein_coding Danio_rerio
ENSG00000020633 RUNX3 runt-related transcription factor 3 protein_coding Homo_sapiens

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