C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: carbamoyl-phosphate synthase 1, mitochondrial
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000021826 CPS1 9606 + 2:210477682-210679107 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000233072 CPS1-001 210556538-210679107 protein_coding
  ENST00000417946 CPS1-002 210477682-210576474 protein_coding
  ENST00000430249 CPS1-011 210477709-210679107 protein_coding
  ENST00000451903 CPS1-003 210593366-210679107 protein_coding
  ENST00000467353 CPS1-006 210604965-210606771 retained_intron
  ENST00000470791 CPS1-008 210658383-210663146 retained_intron
  ENST00000479988 CPS1-004 210671615-210679107 retained_intron
  ENST00000497121 CPS1-007 210631228-210647934 processed_transcript
  ENST00000497163 CPS1-005 210577155-210579800 retained_intron
  ENST00000518043 CPS1-010 210477682-210576474 protein_coding
  ENST00000523702 CPS1-009 210477690-210577493 protein_coding
  ENST00000619804 CPS1-201 210556734-210599555 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000233072ENST00000417946ENST00000430249ENST00000451903ENST00000479988ENST00000619804
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000233072 N/A N/A N/A 0.165±0.04 1.392±0.00 N/A N/A 382.814±0.00 N/A N/A N/A N/A 0.204±0.03 N/A
ENST00000417946 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.112±0.00 N/A N/A N/A
ENST00000430249 0.381±0.00 0.062±0.00 0.285±0.00 0.379±0.00 0.341±0.00 0.095±0.00 0.156±0.11 30.408±29.81 83.066±0.00 0.194±0.09 0.076±0.00 0.353±0.20 0.133±0.00 0.876±0.02
ENST00000451903 N/A 0.193±0.00 N/A N/A N/A 0.239±0.00 0.350±0.00 N/A N/A N/A 0.082±0.05 N/A N/A 3.905±0.08
ENST00000479988 0.070±0.00 N/A N/A N/A N/A N/A N/A N/A N/A 0.085±0.00 N/A 0.029±0.00 N/A N/A
ENST00000619804 N/A N/A 0.537±0.00 1.994±0.00 0.822±0.29 0.680±0.00 0.404±0.00 284.413±0.00 0.620±0.00 N/A N/A N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0006P4 CIL_0006P4_0001 CGP 2:210431249-210679107
CIL_000164 CIL_000164_0001 CGP 2:210477682-212538841

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000050 NAS urea cycle
GO:0001101 IEA response to acid
GO:0001889 IEA liver development
GO:0003824 IEA catalytic activity
GO:0004087 IMP carbamoyl-phosphate synthase (ammonia) activity
GO:0004175 IEA endopeptidase activity
GO:0005509 IEA calcium ion binding
GO:0005515 IPI protein binding
GO:0005524 IEA ATP binding
GO:0005543 IEA phospholipid binding
GO:0005634 IEA nucleus
GO:0005737 IEA cytoplasm
GO:0005739 IEA mitochondrion
GO:0005743 IEA mitochondrial inner membrane
GO:0005759 TAS mitochondrial matrix
GO:0005980 IMP glycogen catabolic process
GO:0006508 IEA proteolysis
GO:0006543 IEA glutamine catabolic process
GO:0006807 IEA nitrogen compound metabolic process
GO:0007494 IEA midgut development
GO:0008152 IEA metabolic process
GO:0008716 IEA D-alanine-D-alanine ligase activity
GO:0009636 IEA response to toxic substance
GO:0010043 IEA response to zinc ion
GO:0014075 IEA response to amine
GO:0016595 IEA glutamate binding
GO:0019240 NAS citrulline biosynthetic process
GO:0019433 IMP triglyceride catabolic process
GO:0032094 IEA response to food
GO:0032403 IEA protein complex binding
GO:0032496 IDA response to lipopolysaccharide
GO:0033762 IEA response to glucagon
GO:0034201 IEA response to oleic acid
GO:0034641 TAS cellular nitrogen compound metabolic process
GO:0042493 IEA response to drug
GO:0042594 IEA response to starvation
GO:0042645 IDA mitochondrial nucleoid
GO:0043200 IEA response to amino acid
GO:0043234 IEA protein complex
GO:0044281 TAS small molecule metabolic process
GO:0044344 IEA cellular response to fibroblast growth factor stimulus
GO:0045909 IMP positive regulation of vasodilation
GO:0046209 IMP nitric oxide metabolic process
GO:0046872 IEA metal ion binding
GO:0048545 IEA response to steroid hormone
GO:0050667 IDA homocysteine metabolic process
GO:0051384 IEA response to glucocorticoid
GO:0051591 IEA response to cAMP
GO:0055081 IEA anion homeostasis
GO:0060416 IEA response to growth hormone
GO:0070365 IEA hepatocyte differentiation
GO:0070409 IMP:IEA carbamoyl phosphate biosynthetic process
GO:0071320 IEA cellular response to cAMP
GO:0071377 IEA cellular response to glucagon stimulus
GO:0071400 IEA cellular response to oleic acid
GO:0071548 IEA response to dexamethasone
GO:0072341 IDA modified amino acid binding

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000020028 cps1 carbamoyl-phosphate synthase 1, mitochondrial protein_coding Danio_rerio
ENSMUSG00000025991 Cps1 carbamoyl-phosphate synthetase 1 protein_coding Mus_musculus

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