C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: four and a half LIM domains 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000022267 FHL1 9606 + X:136147400-136211359 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000345434 FHL1-002 136169926-136211359 protein_coding
  ENST00000370674 FHL1-007 136204721-136209954 protein_coding
  ENST00000370676 FHL1-003 136197026-136210067 protein_coding
  ENST00000370683 FHL1-004 136196773-136211359 protein_coding
  ENST00000370690 FHL1-001 136147465-136211359 protein_coding
  ENST00000394153 FHL1-201 136169637-136211359 protein_coding
  ENST00000394155 FHL1-202 136147400-136211359 protein_coding
  ENST00000420362 FHL1-006 136147666-136208566 protein_coding
  ENST00000434885 FHL1-010 136168194-136208575 protein_coding
  ENST00000449474 FHL1-013 136169891-136207883 protein_coding
  ENST00000452016 FHL1-008 136167004-136208575 protein_coding
  ENST00000456445 FHL1-012 136169676-136208570 protein_coding
  ENST00000458357 FHL1-011 136148111-136207925 protein_coding
  ENST00000477080 FHL1-009 136204909-136207661 processed_transcript
  ENST00000477204 FHL1-005 136197063-136207551 processed_transcript
  ENST00000535737 FHL1-203 136148578-136211359 protein_coding
  ENST00000539015 FHL1-204 136196754-136211359 protein_coding
  ENST00000543669 FHL1-205 136169296-136211359 protein_coding
  ENST00000618438 FHL1-206 136147400-136211359 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000345434ENST00000370676ENST00000370683ENST00000370690ENST00000394155ENST00000449474ENST00000458357ENST00000539015ENST00000618438
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000345434 N/A N/A N/A 13.792±10.16 N/A N/A N/A N/A N/A 3.661±0.00 N/A 7.618±0.00 N/A 5.563±0.00
ENST00000370676 N/A N/A N/A N/A 13.525±0.00 N/A 36.666±0.00 N/A 48.747±0.00 N/A 883.236±68.85 N/A N/A N/A
ENST00000370683 N/A N/A 1.372±0.00 N/A 17.611±0.00 20.828±0.00 22.087±0.00 N/A 64.392±0.00 10.447±0.00 720.700±0.00 N/A N/A N/A
ENST00000370690 73.124±0.00 51.292±0.00 N/A 11.171±6.61 108.221±100.08 214.592±0.00 242.975±0.00 22.353±0.00 6.163±0.00 108.273±100.02 N/A 23.183±13.09 14.562±5.47 46.582±24.42
ENST00000394155 N/A N/A N/A 2.843±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000449474 N/A N/A N/A N/A N/A N/A N/A 3.255±0.00 N/A N/A N/A N/A N/A N/A
ENST00000458357 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 7.022±0.00 20.994±0.00 38.201±0.00
ENST00000539015 77.772±0.00 N/A N/A N/A 136.338±0.00 N/A N/A N/A N/A N/A 1246.110±0.00 6.720±0.90 N/A N/A
ENST00000618438 N/A N/A 1.502±0.00 N/A N/A N/A N/A 2.484±0.00 N/A N/A N/A 1.034±0.00 N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0000PQ CIL_0000PQ_0003 CGP X:135985439-136211359
CIL_0000PP CIL_0000PP_0002 CGP X:136147400-136256482

Gene Ontology
GO IDEvidence TypeGO Description
GO:0003254 IDA regulation of membrane depolarization
GO:0003674 ND molecular_function
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005737 IDA cytoplasm
GO:0005886 IDA plasma membrane
GO:0005925 IDA focal adhesion
GO:0007517 NAS muscle organ development
GO:0008270 IEA zinc ion binding
GO:0009887 NAS organ morphogenesis
GO:0010972 IDA negative regulation of G2/M transition of mitotic cell cycle
GO:0030154 IEA cell differentiation
GO:0030308 IDA negative regulation of cell growth
GO:0043268 IDA positive regulation of potassium ion transport
GO:0044325 IPI ion channel binding
GO:1901016 IDA regulation of potassium ion transmembrane transporter activity
GO:2000134 IDA negative regulation of G1/S transition of mitotic cell cycle

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000056653 fhl1b four and a half LIM domains 1b protein_coding Danio_rerio
ENSDARG00000071498 fhl1a four and a half LIM domains 1a protein_coding Danio_rerio
ENSMUSG00000023092 Fhl1 four and a half LIM domains 1 protein_coding Mus_musculus

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