C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: tumor necrosis factor receptor superfamily, member 1B
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000028137 TNFRSF1B 9606 + 1:12167003-12209228 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000376259 TNFRSF1B-001 12167003-12209228 protein_coding
  ENST00000489921 TNFRSF1B-003 12191838-12193008 processed_transcript
  ENST00000492361 TNFRSF1B-002 12167003-12209228 processed_transcript
  ENST00000536782 TNFRSF1B-201 12167003-12192358 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000376259ENST00000489921ENST00000492361
Transcript ID Adipose Adrenal Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000376259 58.406±0.00 12.605±0.00 1.258±0.75 6.340±5.61 8.764±7.50 5.748±0.00 2.648±0.40 3.634±1.78 15.584±13.59 6.367±0.00 9.685±7.18 28.636±6.31 1.897±1.22
ENST00000489921 N/A N/A N/A 5.188±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000492361 38.930±0.00 38.854±0.00 4.605±0.00 6.590±0.00 8.835±0.00 0.896±0.18 4.855±0.00 4.783±0.00 27.757±0.00 0.861±0.00 10.632±3.54 9.256±3.60 4.183±3.47

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00087H CIL_00087H_0001 VISTA 1:11580820-12184055

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005031 IEA tumor necrosis factor-activated receptor activity
GO:0005515 IPI:IEA protein binding
GO:0005576 IEA extracellular region
GO:0005634 IEA nucleus
GO:0005886 IEA plasma membrane
GO:0006954 IEA inflammatory response
GO:0006955 IEA immune response
GO:0007166 IEA cell surface receptor signaling pathway
GO:0007568 IEA aging
GO:0008630 IEA intrinsic apoptotic signaling pathway in response to DNA damage
GO:0016020 IEA membrane
GO:0016021 IEA integral component of membrane
GO:0030424 IEA axon
GO:0031625 IPI ubiquitin protein ligase binding
GO:0032496 IEA response to lipopolysaccharide
GO:0033209 IEA tumor necrosis factor-mediated signaling pathway
GO:0043025 IEA neuronal cell body
GO:0043196 IEA varicosity
GO:0045121 IDA membrane raft
GO:0048471 IEA perinuclear region of cytoplasm
GO:0050728 IEA negative regulation of inflammatory response
GO:0050779 IEA RNA destabilization
GO:0051044 IMP positive regulation of membrane protein ectodomain proteolysis
GO:0071222 IMP cellular response to lipopolysaccharide
GO:0071363 IEA cellular response to growth factor stimulus
GO:0097191 IEA extrinsic apoptotic signaling pathway

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000070165 tnfrsf1b tumor necrosis factor receptor superfamily, member 1B protein_coding Danio_rerio
ENSMUSG00000028599 Tnfrsf1b tumor necrosis factor receptor superfamily, member 1b protein_coding Mus_musculus

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