C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: POU class 2 homeobox 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000028277 POU2F2 9606 - 19:42086110-42196585 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000342301 POU2F2-002 42089353-42132476 protein_coding
  ENST00000389341 POU2F2-001 42086110-42132478 protein_coding
  ENST00000524801 POU2F2-011 42116783-42176025 processed_transcript
  ENST00000526816 POU2F2-005 42089790-42132427 protein_coding
  ENST00000526831 POU2F2-010 42095809-42116887 protein_coding
  ENST00000528894 POU2F2-009 42095788-42132391 protein_coding
  ENST00000529067 POU2F2-003 42090205-42132465 protein_coding
  ENST00000529952 POU2F2-004 42091815-42132473 protein_coding
  ENST00000530982 POU2F2-013 42099329-42132412 retained_intron
  ENST00000531773 POU2F2-007 42099715-42123229 processed_transcript
  ENST00000532176 POU2F2-012 42117266-42196585 processed_transcript
  ENST00000533548 POU2F2-014 42091160-42095405 protein_coding
  ENST00000534559 POU2F2-006 42091149-42132456 nonsense_mediated_decay
  ENST00000558596 POU2F2-018 42122093-42122580 protein_coding
  ENST00000560398 POU2F2-017 42091230-42132419 protein_coding
  ENST00000560558 POU2F2-016 42089553-42132419 protein_coding
  ENST00000560804 POU2F2-015 42091078-42132399 protein_coding
  ENST00000598842 POU2F2-008 42093467-42095611 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdrenalBladderBrainBreastColonHeartKidneyLiverLungMusclePlacentaTestisENST00000389341ENST00000524801ENST00000526816ENST00000526831ENST00000528894ENST00000529067ENST00000530982ENST00000533548ENST00000560398ENST00000598842
Transcript ID Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Placenta Testis
ENST00000389341 8.462±0.00 N/A N/A N/A 0.125±0.00 N/A 0.029±0.00 N/A N/A N/A N/A N/A
ENST00000524801 N/A N/A 0.593±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000526816 N/A N/A 0.462±0.00 N/A N/A 0.103±0.00 N/A N/A N/A N/A 0.664±0.07 N/A
ENST00000526831 N/A N/A N/A N/A N/A N/A 0.289±0.00 N/A N/A 0.211±0.00 N/A N/A
ENST00000528894 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 2.694±0.00 N/A
ENST00000529067 N/A 0.012±0.00 N/A 0.374±0.00 0.331±0.00 0.011±0.00 N/A N/A 1.507±0.00 N/A N/A 0.892±0.00
ENST00000530982 N/A N/A N/A N/A 1.617±0.00 N/A N/A N/A N/A N/A N/A N/A
ENST00000533548 N/A N/A N/A N/A N/A 0.338±0.00 N/A N/A N/A N/A N/A N/A
ENST00000560398 N/A N/A N/A N/A N/A N/A N/A 0.229±0.00 N/A N/A N/A N/A
ENST00000598842 N/A N/A N/A 0.563±0.00 N/A N/A N/A N/A N/A N/A N/A 4.583±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0003DQ CIL_0003DQ_0001 CGP 19:42068477-42196585
CIL_0003X4 CIL_0003X4_0001 CGP 19:42086110-42220140

Gene Ontology
GO IDEvidence TypeGO Description
GO:0002335 IEA mature B cell differentiation
GO:0002380 IEA immunoglobulin secretion involved in immune response
GO:0003677 IEA DNA binding
GO:0003700 IEA sequence-specific DNA binding transcription factor activity
GO:0005634 IEA nucleus
GO:0005737 IEA cytoplasm
GO:0006355 IEA regulation of transcription, DNA-templated
GO:0006366 TAS transcription from RNA polymerase II promoter
GO:0006959 TAS humoral immune response
GO:0019904 IEA protein domain specific binding
GO:0043565 IEA sequence-specific DNA binding
GO:0045893 IEA positive regulation of transcription, DNA-templated
GO:0048305 IEA immunoglobulin secretion
GO:0048469 IEA cell maturation

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000019658 pou2f2b POU domain, class 2, transcription factor 2b protein_coding Danio_rerio
ENSDARG00000036816 pou2f2a POU domain, class 2, transcription factor 2a protein_coding Danio_rerio
ENSMUSG00000008496 Pou2f2 POU domain, class 2, transcription factor 2 protein_coding Mus_musculus

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