C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: POU domain, class 2, transcription factor 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000008496 Pou2f2 10090 - 7:25087344-25159922 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000098679 Pou2f2-003 25092476-25132488 protein_coding
  ENSMUST00000108413 Pou2f2-007 25092656-25132488 protein_coding
  ENSMUST00000108415 Pou2f2-005 25087344-25132488 protein_coding
  ENSMUST00000108416 Pou2f2-008 25092520-25132488 protein_coding
  ENSMUST00000108417 Pou2f2-002 25092520-25132488 protein_coding
  ENSMUST00000108418 Pou2f2-004 25092520-25132477 protein_coding
  ENSMUST00000147146 Pou2f2-009 25100021-25120858 protein_coding
  ENSMUST00000175754 Pou2f2-006 25120618-25159922 retained_intron
  ENSMUST00000175774 Pou2f2-001 25087344-25132488 protein_coding
  ENSMUST00000176408 Pou2f2-010 25093248-25132512 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000098679ENSMUST00000108413ENSMUST00000108415ENSMUST00000108416ENSMUST00000108417ENSMUST00000108418ENSMUST00000147146ENSMUST00000175774ENSMUST00000176408
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000098679 N/A N/A N/A N/A N/A N/A 0.050±0.01 N/A N/A N/A N/A N/A N/A N/A
ENSMUST00000108413 N/A N/A N/A N/A 3.699±0.00 N/A N/A 0.143±0.00 0.377±0.00 N/A N/A 0.779±0.12 N/A N/A
ENSMUST00000108415 0.266±0.05 0.102±0.00 N/A N/A 1.305±0.61 0.108±0.00 N/A 0.137±0.00 0.111±0.05 0.266±0.04 0.051±0.07 0.302±0.14 0.017±0.00 N/A
ENSMUST00000108416 N/A 0.282±0.00 N/A N/A N/A 0.549±0.00 N/A N/A N/A N/A N/A 0.300±0.00 0.118±0.00 N/A
ENSMUST00000108417 0.313±0.00 0.512±0.12 N/A N/A 3.606±1.55 0.571±0.29 N/A 0.310±0.12 0.085±0.00 0.900±0.12 N/A 0.432±0.10 N/A N/A
ENSMUST00000108418 0.375±0.00 0.327±0.13 N/A 4.302±0.00 2.733±0.75 0.428±0.20 N/A 0.304±0.21 0.316±0.03 0.718±0.08 N/A 0.417±0.15 0.102±0.00 1.585±0.13
ENSMUST00000147146 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.903±0.20 N/A N/A
ENSMUST00000175774 0.428±0.08 0.146±0.05 0.128±0.02 4.560±0.00 1.105±0.58 0.297±0.12 0.213±0.14 0.308±0.08 0.373±0.21 0.575±0.19 0.123±0.18 0.255±0.08 0.083±0.03 N/A
ENSMUST00000176408 N/A N/A N/A N/A N/A N/A N/A 0.137±0.00 N/A N/A N/A 0.242±0.00 N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0003DQ CIL_0003DQ_0002 CGP 7:25077205-25159922
CIL_0003X4 CIL_0003X4_0002 CGP 7:25087344-25219859

Gene Ontology
GO IDEvidence TypeGO Description
GO:0002335 IMP mature B cell differentiation
GO:0002380 IMP immunoglobulin secretion involved in immune response
GO:0003677 IDA DNA binding
GO:0003700 IDA sequence-specific DNA binding transcription factor activity
GO:0005634 IDA nucleus
GO:0005737 IEA cytoplasm
GO:0006351 IEA transcription, DNA-templated
GO:0006355 IDA regulation of transcription, DNA-templated
GO:0019904 IPI protein domain specific binding
GO:0043565 IDA sequence-specific DNA binding
GO:0045893 IDA positive regulation of transcription, DNA-templated
GO:0048305 IMP immunoglobulin secretion
GO:0048469 IMP cell maturation

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000019658 pou2f2b POU domain, class 2, transcription factor 2b protein_coding Danio_rerio
ENSDARG00000036816 pou2f2a POU domain, class 2, transcription factor 2a protein_coding Danio_rerio
ENSG00000028277 POU2F2 POU class 2 homeobox 2 protein_coding Homo_sapiens

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