C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: BCL2-antagonist/killer 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000030110 BAK1 9606 - 6:33572547-33580293 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000360661 BAK1-201 33572547-33580293 protein_coding
  ENST00000374467 BAK1-002 33572552-33580242 protein_coding
  ENST00000442998 BAK1-202 33572547-33580293 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000360661ENST00000374467ENST00000442998
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000360661 2.363±0.00 N/A 0.507±0.00 N/A 2.163±0.00 0.958±0.16 0.898±0.00 0.600±0.00 N/A N/A N/A 2.949±1.80 0.769±0.00 3.107±0.00
ENST00000374467 2.413±0.00 12.534±0.00 N/A 1.098±0.65 2.573±1.93 4.707±2.21 4.544±0.00 14.954±0.00 1.987±1.53 6.038±4.96 2.308±0.82 8.293±4.05 11.785±4.74 3.047±0.50
ENST00000442998 N/A N/A N/A 0.559±0.00 N/A N/A 0.313±0.00 N/A N/A N/A N/A N/A 0.736±0.00 N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_000255 CIL_000255_0001 CGP 6:33572547-33696574

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001776 IEA leukocyte homeostasis
GO:0001782 IEA B cell homeostasis
GO:0001783 IEA B cell apoptotic process
GO:0001836 IDA release of cytochrome c from mitochondria
GO:0001974 IEA blood vessel remodeling
GO:0002262 IEA myeloid cell homeostasis
GO:0002352 IEA B cell negative selection
GO:0005515 IPI protein binding
GO:0005622 IEA intracellular
GO:0005739 IDA mitochondrion
GO:0005741 IBA mitochondrial outer membrane
GO:0005783 IEA endoplasmic reticulum
GO:0005829 IEA cytosol
GO:0006915 TAS apoptotic process
GO:0006919 IEA activation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0007420 IEA brain development
GO:0007568 IEA aging
GO:0008053 IEA mitochondrial fusion
GO:0008283 IEA cell proliferation
GO:0008285 IEA negative regulation of cell proliferation
GO:0008630 IBA intrinsic apoptotic signaling pathway in response to DNA damage
GO:0008635 IEA activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c
GO:0009620 IEA response to fungus
GO:0010046 IEA response to mycotoxin
GO:0010225 IEA response to UV-C
GO:0010248 IDA establishment or maintenance of transmembrane electrochemical gradient
GO:0010332 IEA response to gamma radiation
GO:0010524 IEA positive regulation of calcium ion transport into cytosol
GO:0010629 IEA negative regulation of gene expression
GO:0014070 IEA response to organic cyclic compound
GO:0016020 IEA membrane
GO:0031018 IEA endocrine pancreas development
GO:0031072 IEA heat shock protein binding
GO:0031100 IEA organ regeneration
GO:0031307 ISS integral component of mitochondrial outer membrane
GO:0031966 IEA mitochondrial membrane
GO:0032469 TAS endoplasmic reticulum calcium ion homeostasis
GO:0032471 IEA negative regulation of endoplasmic reticulum calcium ion concentration
GO:0033137 IEA negative regulation of peptidyl-serine phosphorylation
GO:0034644 ISS cellular response to UV
GO:0035108 IEA limb morphogenesis
GO:0042493 IEA response to drug
GO:0042542 IEA response to hydrogen peroxide
GO:0042802 IPI identical protein binding
GO:0042803 IBA protein homodimerization activity
GO:0042981 IEA regulation of apoptotic process
GO:0043065 IMP positive regulation of apoptotic process
GO:0043496 IDA regulation of protein homodimerization activity
GO:0043497 IDA regulation of protein heterodimerization activity
GO:0044346 IEA fibroblast apoptotic process
GO:0045471 IEA response to ethanol
GO:0045862 IDA positive regulation of proteolysis
GO:0046872 IEA metal ion binding
GO:0046902 IDA regulation of mitochondrial membrane permeability
GO:0046930 IDA pore complex
GO:0046982 IPI protein heterodimerization activity
GO:0048597 IEA post-embryonic camera-type eye morphogenesis
GO:0048872 IEA homeostasis of number of cells
GO:0051087 IEA chaperone binding
GO:0051400 IEA BH domain binding
GO:0051726 IEA regulation of cell cycle
GO:0051881 IDA regulation of mitochondrial membrane potential
GO:0060068 IEA vagina development
GO:0070059 IEA intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress
GO:0070242 IEA thymocyte apoptotic process
GO:0071260 IEP cellular response to mechanical stimulus
GO:0090200 IEA positive regulation of release of cytochrome c from mitochondria
GO:0097190 IMP apoptotic signaling pathway
GO:0097192 IBA extrinsic apoptotic signaling pathway in absence of ligand
GO:0097193 TAS intrinsic apoptotic signaling pathway
GO:0097202 IDA activation of cysteine-type endopeptidase activity
GO:1900103 IMP positive regulation of endoplasmic reticulum unfolded protein response
GO:1901030 TAS positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway
GO:1902262 IEA apoptotic process involved in patterning of blood vessels

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSMUSG00000057789 Bak1 BCL2-antagonist/killer 1 protein_coding Mus_musculus

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