C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: fucosyltransferase 8 (alpha (1,6) fucosyltransferase)
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000033170 FUT8 9606 + 14:65410592-65744121 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000342677 FUT8-005 65411865-65743142 nonsense_mediated_decay
  ENST00000358307 FUT8-002 65413008-65743142 protein_coding
  ENST00000360689 FUT8-001 65410592-65744121 protein_coding
  ENST00000394586 FUT8-003 65411122-65743142 protein_coding
  ENST00000549235 FUT8-008 65411891-65458188 processed_transcript
  ENST00000553924 FUT8-013 65413006-65561610 protein_coding
  ENST00000554610 FUT8-007 65413022-65561697 protein_coding
  ENST00000554667 FUT8-012 65488318-65561702 protein_coding
  ENST00000554765 FUT8-014 65636517-65721858 processed_transcript
  ENST00000555559 FUT8-010 65411936-65561685 protein_coding
  ENST00000556292 FUT8-009 65413069-65458188 processed_transcript
  ENST00000556518 FUT8-006 65411863-65561652 protein_coding
  ENST00000557164 FUT8-004 65411874-65742936 protein_coding
  ENST00000557338 FUT8-011 65413019-65561715 protein_coding
  ENST00000557536 FUT8-015 65636516-65721912 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000342677ENST00000358307ENST00000360689ENST00000394586ENST00000557164
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000342677 1.260±0.00 2.157±0.00 0.757±0.00 7.677±3.86 8.432±6.44 2.902±1.18 1.020±0.31 1.074±0.57 3.772±3.56 3.501±0.99 0.183±0.00 5.127±2.52 7.706±4.56 7.040±2.27
ENST00000358307 N/A N/A N/A N/A N/A N/A N/A 0.804±0.00 0.073±0.00 N/A N/A N/A 1.424±0.00 N/A
ENST00000360689 N/A N/A N/A 2.492±0.00 N/A 0.274±0.00 0.169±0.00 N/A N/A N/A N/A 0.470±0.00 N/A 1.063±0.00
ENST00000394586 N/A N/A N/A N/A N/A 1.655±0.00 N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000557164 2.365±0.00 3.487±0.00 1.997±0.00 8.111±0.68 5.297±2.26 2.561±0.92 1.167±0.07 1.960±0.00 1.623±1.34 1.961±0.92 1.551±0.00 5.358±1.14 4.324±2.61 4.994±1.76

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0001PC CIL_0001PC_0001 CGP 14:65006174-65744121
CIL_0001KA CIL_0001KA_0002 CGP 14:65410592-67181803

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000139 TAS Golgi membrane
GO:0001701 NAS in utero embryonic development
GO:0005515 IEA protein binding
GO:0005737 IDA cytoplasm
GO:0005794 NAS Golgi apparatus
GO:0006487 TAS protein N-linked glycosylation
GO:0006491 TAS N-glycan processing
GO:0007179 IEA transforming growth factor beta receptor signaling pathway
GO:0007229 IEA integrin-mediated signaling pathway
GO:0007585 IEA respiratory gaseous exchange
GO:0008152 IEA metabolic process
GO:0008424 TAS glycoprotein 6-alpha-L-fucosyltransferase activity
GO:0009312 TAS oligosaccharide biosynthetic process
GO:0016020 IDA membrane
GO:0016021 IEA integral component of membrane
GO:0016477 IEA cell migration
GO:0016757 IEA transferase activity, transferring glycosyl groups
GO:0017124 IEA SH3 domain binding
GO:0018279 IDA protein N-linked glycosylation via asparagine
GO:0032580 IEA Golgi cisterna membrane
GO:0033578 IEA protein glycosylation in Golgi
GO:0036065 IEA fucosylation
GO:0036071 IEA N-glycan fucosylation
GO:0042355 NAS L-fucose catabolic process
GO:0043112 IEA receptor metabolic process
GO:0043687 TAS post-translational protein modification
GO:0044267 TAS cellular protein metabolic process
GO:0046368 IDA GDP-L-fucose metabolic process
GO:0046921 IEA alpha-(1->6)-fucosyltransferase activity
GO:0070062 IDA extracellular vesicular exosome

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000015449 fut8a fucosyltransferase 8a (alpha (1,6) fucosyltransferase) protein_coding Danio_rerio
ENSDARG00000088117 FUT8 (2 of 2) fucosyltransferase 8 (alpha (1,6) fucosyltransferase) protein_coding Danio_rerio
ENSMUSG00000021065 Fut8 fucosyltransferase 8 protein_coding Mus_musculus

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