C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: ATPase, H+ transporting, lysosomal V0 subunit a1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000033627 ATP6V0A1 9606 + 17:42458844-42522611 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000264649 ATP6V0A1-004 42458880-42522582 protein_coding
  ENST00000343619 ATP6V0A1-006 42458888-42522611 protein_coding
  ENST00000393829 ATP6V0A1-001 42458844-42521485 protein_coding
  ENST00000537728 ATP6V0A1-003 42458878-42521394 protein_coding
  ENST00000544137 ATP6V0A1-201 42458904-42522578 protein_coding
  ENST00000585525 ATP6V0A1-005 42458888-42521291 protein_coding
  ENST00000585828 ATP6V0A1-007 42507335-42522582 retained_intron
  ENST00000586001 ATP6V0A1-016 42477643-42478949 retained_intron
  ENST00000586201 ATP6V0A1-025 42500813-42521444 protein_coding
  ENST00000586315 ATP6V0A1-021 42490537-42494589 retained_intron
  ENST00000587299 ATP6V0A1-027 42520383-42521785 processed_transcript
  ENST00000587375 ATP6V0A1-018 42470182-42480965 retained_intron
  ENST00000587510 ATP6V0A1-023 42500782-42513941 nonsense_mediated_decay
  ENST00000587797 ATP6V0A1-010 42520335-42522577 processed_transcript
  ENST00000587824 ATP6V0A1-012 42459069-42470187 protein_coding
  ENST00000587882 ATP6V0A1-019 42480263-42487353 retained_intron
  ENST00000588138 ATP6V0A1-022 42501242-42521045 protein_coding
  ENST00000588629 ATP6V0A1-002 42458858-42471439 retained_intron
  ENST00000588806 ATP6V0A1-024 42513442-42521159 retained_intron
  ENST00000588901 ATP6V0A1-015 42458878-42478510 nonsense_mediated_decay
  ENST00000589213 ATP6V0A1-013 42460183-42468093 protein_coding
  ENST00000589727 ATP6V0A1-014 42458941-42483092 protein_coding
  ENST00000589759 ATP6V0A1-020 42481286-42490608 processed_transcript
  ENST00000592324 ATP6V0A1-017 42468036-42480717 protein_coding
  ENST00000592831 ATP6V0A1-009 42517927-42522578 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000264649ENST00000343619ENST00000393829ENST00000537728ENST00000544137ENST00000585525ENST00000585828ENST00000587797ENST00000587824ENST00000588629ENST00000592831
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000264649 7.000±0.00 2.736±0.00 N/A 29.574±0.00 5.004±0.00 7.250±0.00 3.698±0.00 11.160±0.00 1.788±0.00 2.976±0.00 12.108±10.17 2.836±0.97 1.814±0.00 9.275±0.00
ENST00000343619 5.120±0.00 N/A 2.721±0.00 33.554±4.67 3.982±0.00 3.722±0.00 0.780±0.25 1.235±0.00 2.484±0.29 N/A N/A 3.861±0.00 N/A 2.586±0.00
ENST00000393829 N/A N/A 4.282±0.00 N/A 2.384±0.00 N/A N/A 2.090±0.00 3.708±0.00 N/A N/A 4.727±0.17 N/A N/A
ENST00000537728 N/A N/A 3.090±0.00 N/A N/A 4.530±0.00 N/A N/A N/A N/A N/A 4.260±0.00 3.324±0.00 2.648±0.00
ENST00000544137 N/A 1.514±0.00 N/A N/A N/A 4.241±0.00 1.878±0.00 1.410±0.00 2.094±0.00 N/A 13.761±0.00 4.243±0.00 4.154±0.28 4.270±0.00
ENST00000585525 N/A N/A N/A N/A N/A N/A 1.802±0.00 N/A N/A N/A N/A N/A N/A N/A
ENST00000585828 N/A 3.468±0.00 N/A N/A 6.423±0.00 N/A N/A 16.528±0.00 6.699±0.00 7.045±0.00 9.284±6.02 11.176±2.50 6.546±0.00 10.219±0.00
ENST00000587797 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 5.000±0.00 N/A N/A
ENST00000587824 N/A N/A N/A N/A N/A N/A 3.675±0.00 N/A N/A 17.285±0.00 5.564±0.00 N/A N/A N/A
ENST00000588629 N/A N/A N/A N/A N/A N/A 0.732±0.00 N/A N/A N/A N/A N/A N/A N/A
ENST00000592831 N/A 1.115±0.00 N/A N/A N/A 1.738±0.00 N/A N/A N/A 1.987±0.00 N/A 3.668±1.66 N/A 2.936±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00046F CIL_00046F_0001 CGP 17:42402452-42522611
CIL_00046D CIL_00046D_0001 CGP 17:42458844-42544449

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000220 IEA vacuolar proton-transporting V-type ATPase, V0 domain
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005737 IDA cytoplasm
GO:0005794 IDA Golgi apparatus
GO:0005886 IDA plasma membrane
GO:0006879 TAS cellular iron ion homeostasis
GO:0008286 TAS insulin receptor signaling pathway
GO:0010008 TAS endosome membrane
GO:0015078 IEA hydrogen ion transmembrane transporter activity
GO:0015991 IEA ATP hydrolysis coupled proton transport
GO:0016021 IEA integral component of membrane
GO:0030670 TAS phagocytic vesicle membrane
GO:0033179 IEA proton-transporting V-type ATPase, V0 domain
GO:0033572 TAS transferrin transport
GO:0043231 IDA intracellular membrane-bounded organelle
GO:0051117 IPI ATPase binding
GO:0051701 TAS interaction with host
GO:0055085 TAS transmembrane transport
GO:0070062 IDA extracellular vesicular exosome
GO:0090382 TAS phagosome maturation

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000015174 atp6v0a1b ATPase, H+ transporting, lysosomal V0 subunit a isoform 1b protein_coding Danio_rerio
ENSDARG00000020847 atp6v0a1a ATPase, H+ transporting, lysosomal V0 subunit a isoform 1a protein_coding Danio_rerio
ENSMUSG00000019302 Atp6v0a1 ATPase, H+ transporting, lysosomal V0 subunit A1 protein_coding Mus_musculus

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