Institute of Cardiovascular Regeneration Webtool Repository

C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Accession	Transcript Name	Contained in Gene	Tax ID	Strand	Position	Biotype
Transcript Info
Description:	apoptosis-inducing factor, mitochondrion-associated, 2
ENST00000307864	AIFM2-001	ENSG00000042286	9606	-	10:70112271-70132934	protein_coding

Expression Patterns

Transcript ID	Adipose	Adrenal	Brain	Breast	Colon	Heart	Kidney	Liver	Lung	Muscle	Ovary	Placenta	Testis
ENST00000307864	17.072±0.00	3.095±0.00	1.149±0.78	22.253±20.50	4.004±0.00	3.031±0.00	7.646±0.00	3.286±2.70	2.243±1.88	2.059±0.00	6.078±2.71	3.079±0.38	3.193±0.68

Conserved Regions
Gene is not located within a conserved region.

Gene Ontology
GO ID	Evidence Type	GO Description
GO:0003677	IDA	DNA binding
GO:0004174	IDA	electron-transferring-flavoprotein dehydrogenase activity
GO:0005615	IDA	extracellular space
GO:0005737	IDA	cytoplasm
GO:0005739	IDA	mitochondrion
GO:0005741	IDA	mitochondrial outer membrane
GO:0005811	IDA	lipid particle
GO:0005829	IDA	cytosol
GO:0008137	IBA	NADH dehydrogenase (ubiquinone) activity
GO:0008637	IDA	apoptotic mitochondrial changes
GO:0016021	IEA	integral component of membrane
GO:0016491	IEA	oxidoreductase activity
GO:0043065	IBA	positive regulation of apoptotic process
GO:0050660	IDA:IEA	flavin adenine dinucleotide binding
GO:0055114	IEA	oxidation-reduction process

Homologs
ENSEMBL Accession	Gene Name	Biotype	Species	E-Value	Bit Score
ENSMUST00000099706	Aifm2-003	protein_coding	Mus_musculus	0	1256
ENSMUST00000067857	Aifm2-002	protein_coding	Mus_musculus	0	1256
ENSMUST00000105455	Aifm2-001	protein_coding	Mus_musculus	0	1256
ENSMUST00000080099	Aifm2-004	protein_coding	Mus_musculus	0	1088
ENSMUST00000131361	Aifm2-005	retained_intron	Mus_musculus	0	507
ENSMUST00000140664	Aifm2-006	retained_intron	Mus_musculus	0	405
ENSMUST00000022235	Htr1a-201	protein_coding	Mus_musculus	0.0003	53

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