C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000043462 LCP2 9606 - 5:170246237-170298227 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000046794 LCP2-001 170246237-170298227 protein_coding
  ENST00000519149 LCP2-008 170287717-170297784 retained_intron
  ENST00000519594 LCP2-010 170270500-170297727 retained_intron
  ENST00000520322 LCP2-006 170247572-170251692 retained_intron
  ENST00000520344 LCP2-011 170256557-170267327 protein_coding
  ENST00000521416 LCP2-005 170248300-170267296 protein_coding
  ENST00000522760 LCP2-009 170273781-170297729 retained_intron
  ENST00000522823 LCP2-007 170275625-170297815 retained_intron
  ENST00000523369 LCP2-012 170256526-170258498 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaENST00000046794ENST00000519594ENST00000520322ENST00000520344ENST00000521416ENST00000522760ENST00000522823ENST00000523369
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta
ENST00000046794 2.407±0.00 3.295±0.00 0.201±0.00 0.392±0.26 1.014±0.10 0.205±0.00 0.404±0.00 0.448±0.00 0.371±0.03 N/A 0.113±0.00 0.558±0.06 1.877±0.66
ENST00000519594 N/A N/A 0.899±0.00 N/A 4.247±0.00 2.355±0.00 N/A 1.850±0.00 1.666±0.10 17.352±8.32 N/A 2.531±0.00 6.770±0.00
ENST00000520322 N/A N/A N/A 0.185±0.00 1.196±0.46 0.429±0.00 N/A 0.299±0.00 0.619±0.00 N/A N/A 0.404±0.00 N/A
ENST00000520344 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 1.137±0.00 N/A N/A
ENST00000521416 11.175±0.00 16.699±0.00 0.366±0.00 2.621±2.17 3.281±0.00 2.665±0.00 2.246±0.00 1.548±0.66 1.269±0.21 16.006±0.00 0.964±0.78 2.753±0.82 6.589±2.08
ENST00000522760 N/A N/A N/A N/A N/A N/A 0.984±0.00 1.317±0.00 N/A N/A 0.250±0.00 N/A N/A
ENST00000522823 N/A N/A N/A N/A N/A 2.714±0.00 1.307±0.00 8.817±0.00 N/A 12.715±0.00 N/A N/A N/A
ENST00000523369 N/A N/A 6.658±0.00 3.443±0.00 N/A 8.512±0.00 N/A N/A 9.328±0.00 N/A N/A 5.493±0.00 N/A

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005515 IPI:IEA protein binding
GO:0005829 TAS cytosol
GO:0005911 IEA cell-cell junction
GO:0006955 TAS immune response
GO:0007169 TAS transmembrane receptor protein tyrosine kinase signaling pathway
GO:0007596 TAS blood coagulation
GO:0030168 TAS platelet activation
GO:0038095 TAS Fc-epsilon receptor signaling pathway
GO:0045087 TAS innate immune response
GO:0045576 IEA mast cell activation
GO:0050663 IEA cytokine secretion
GO:0050852 TAS T cell receptor signaling pathway

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000036215 lcp2b lymphocyte cytosolic protein 2b protein_coding Danio_rerio
ENSDARG00000055955 lcp2a lymphocyte cytosolic protein 2a protein_coding Danio_rerio
ENSMUSG00000002699 Lcp2 lymphocyte cytosolic protein 2 protein_coding Mus_musculus

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