C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: desmoglein 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000046604 DSG2 9606 + 18:31498043-31549008 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000261590 DSG2-001 31498043-31549008 protein_coding
  ENST00000585206 DSG2-002 31498220-31522608 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000261590
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000261590 20.011±0.00 1.454±0.00 8.273±0.00 0.146±0.02 12.765±4.29 17.472±9.55 6.745±3.74 7.652±5.42 3.680±1.31 3.996±0.01 0.322±0.02 13.042±6.61 11.915±3.20 1.735±0.07

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0006PL CIL_0006PL_0001 CGP 18:31447795-31549008
CIL_0003TY CIL_0003TY_0001 CGP 18:31498043-31599021

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005509 IEA calcium ion binding
GO:0005886 IDA plasma membrane
GO:0005911 TAS cell-cell junction
GO:0006915 TAS apoptotic process
GO:0006921 TAS cellular component disassembly involved in execution phase of apoptosis
GO:0007155 IDA cell adhesion
GO:0007156 IEA homophilic cell adhesion via plasma membrane adhesion molecules
GO:0009986 IDA cell surface
GO:0016020 IEA membrane
GO:0016021 IEA integral component of membrane
GO:0016324 IEA apical plasma membrane
GO:0016328 IEA lateral plasma membrane
GO:0030057 IEA desmosome
GO:0032570 IEA response to progesterone
GO:0060135 IEA maternal process involved in female pregnancy
GO:0070062 IDA extracellular vesicular exosome
GO:0086005 IMP ventricular cardiac muscle cell action potential
GO:0086069 IMP bundle of His cell to Purkinje myocyte communication
GO:0086091 IMP regulation of heart rate by cardiac conduction

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000039665 CABZ01055869.1 Uncharacterized protein protein_coding Danio_rerio
ENSDARG00000062750 si:ch73-74h11.1 si:ch73-74h11.1 protein_coding Danio_rerio
ENSDARG00000076426 dsg2l desmoglein 2 like protein_coding Danio_rerio
ENSMUSG00000044393 Dsg2 desmoglein 2 protein_coding Mus_musculus

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