C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: breast cancer anti-estrogen resistance 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000050820 BCAR1 9606 - 16:75228187-75268053 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000162330 BCAR1-002 75229030-75251609 protein_coding
  ENST00000393420 BCAR1-008 75229511-75251482 protein_coding
  ENST00000393422 BCAR1-001 75228187-75268053 protein_coding
  ENST00000418647 BCAR1-005 75229159-75266007 protein_coding
  ENST00000420641 BCAR1-003 75229455-75266781 protein_coding
  ENST00000535626 BCAR1-006 75229062-75265948 protein_coding
  ENST00000538440 BCAR1-004 75229103-75266007 protein_coding
  ENST00000542031 BCAR1-009 75229453-75248240 protein_coding
  ENST00000546196 BCAR1-022 75263876-75265215 protein_coding
  ENST00000561970 BCAR1-013 75242776-75250947 protein_coding
  ENST00000562556 BCAR1-007 75229031-75265215 nonsense_mediated_decay
  ENST00000563038 BCAR1-011 75229037-75236503 retained_intron
  ENST00000563323 BCAR1-012 75242840-75266382 protein_coding
  ENST00000563700 BCAR1-014 75243055-75250104 processed_transcript
  ENST00000564028 BCAR1-021 75242615-75251880 protein_coding
  ENST00000564170 BCAR1-018 75236696-75237431 retained_intron
  ENST00000566465 BCAR1-016 75242632-75248943 protein_coding
  ENST00000566982 BCAR1-010 75229037-75238660 processed_transcript
  ENST00000567215 BCAR1-015 75242865-75249966 protein_coding
  ENST00000568864 BCAR1-019 75242611-75264416 protein_coding
  ENST00000569006 BCAR1-020 75242656-75256280 protein_coding
  ENST00000569340 BCAR1-017 75235668-75242702 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000162330ENST00000393420ENST00000393422ENST00000420641ENST00000535626ENST00000538440ENST00000542031ENST00000562556ENST00000563038ENST00000564028ENST00000566465
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000162330 3.147±0.00 3.815±0.00 N/A 1.014±0.00 2.718±1.21 N/A 0.959±0.00 0.228±0.00 3.113±0.00 N/A 1.435±0.00 7.862±4.04 20.263±2.45 10.018±0.00
ENST00000393420 N/A N/A N/A 7.260±0.00 N/A 8.958±0.00 N/A 0.165±0.00 N/A 0.980±0.00 N/A 9.701±0.00 N/A 14.766±0.00
ENST00000393422 N/A N/A N/A N/A N/A N/A N/A N/A 0.369±0.00 N/A N/A N/A N/A N/A
ENST00000420641 9.150±0.00 4.508±0.00 N/A 7.326±0.00 3.990±0.00 N/A N/A N/A N/A N/A N/A 13.670±0.00 11.465±0.00 N/A
ENST00000535626 N/A N/A N/A N/A N/A 0.920±0.00 N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000538440 6.849±0.00 13.159±0.00 N/A 4.965±3.46 8.408±0.00 12.324±0.00 N/A 23.060±0.00 6.753±0.00 0.751±0.00 13.274±0.00 4.576±0.00 22.060±6.67 13.696±0.00
ENST00000542031 N/A N/A 2.399±0.00 N/A 1.240±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000562556 N/A N/A N/A N/A N/A 0.463±0.00 N/A N/A N/A N/A N/A 0.531±0.00 N/A N/A
ENST00000563038 N/A N/A 0.877±0.00 N/A N/A N/A N/A 0.199±0.00 0.777±0.00 N/A 1.052±0.00 N/A N/A N/A
ENST00000564028 N/A N/A 5.105±0.00 N/A N/A N/A N/A 2.274±0.00 N/A N/A N/A N/A N/A N/A
ENST00000566465 N/A N/A N/A N/A N/A 4.660±0.00 2.659±0.00 N/A 4.218±0.00 N/A 5.966±0.00 N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0001S1 CIL_0001S1_0001 CGP 16:75219000-75268053
CIL_00024P CIL_00024P_0001 CGP 16:75228187-75433485

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001558 TAS regulation of cell growth
GO:0001726 IDA ruffle
GO:0004871 IEA signal transducer activity
GO:0005515 IPI:IEA protein binding
GO:0005730 IDA nucleolus
GO:0005737 IDA cytoplasm
GO:0005829 TAS cytosol
GO:0005886 IDA plasma membrane
GO:0005925 IDA:ISS focal adhesion
GO:0007015 IDA actin filament organization
GO:0007155 IEA cell adhesion
GO:0007173 ISS epidermal growth factor receptor signaling pathway
GO:0007186 ISS G-protein coupled receptor signaling pathway
GO:0007229 IDA integrin-mediated signaling pathway
GO:0007596 TAS blood coagulation
GO:0008283 TAS cell proliferation
GO:0008286 ISS insulin receptor signaling pathway
GO:0010595 IDA positive regulation of endothelial cell migration
GO:0015629 IEA actin cytoskeleton
GO:0016477 IDA cell migration
GO:0017124 IEA SH3 domain binding
GO:0019901 IPI protein kinase binding
GO:0030027 IEA lamellipodium
GO:0030168 TAS platelet activation
GO:0030335 IDA positive regulation of cell migration
GO:0035729 IMP cellular response to hepatocyte growth factor stimulus
GO:0042981 TAS regulation of apoptotic process
GO:0048008 ISS platelet-derived growth factor receptor signaling pathway
GO:0048010 IMP vascular endothelial growth factor receptor signaling pathway
GO:0048011 ISS neurotrophin TRK receptor signaling pathway
GO:0048012 IMP hepatocyte growth factor receptor signaling pathway
GO:0050851 IDA antigen receptor-mediated signaling pathway
GO:0050852 NAS T cell receptor signaling pathway
GO:0050853 IDA B cell receptor signaling pathway
GO:0051301 NAS cell division
GO:0060326 IMP cell chemotaxis

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000056525 bcar1 breast cancer anti-estrogen resistance 1 protein_coding Danio_rerio
ENSMUSG00000031955 Bcar1 breast cancer anti-estrogen resistance 1 protein_coding Mus_musculus

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