C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: coagulation factor VII (serum prothrombin conversion accelerator)
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000057593 F7 9606 + 13:113105788-113120681 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000346342 F7-002 113105791-113120031 protein_coding
  ENST00000375581 F7-001 113105807-113120681 protein_coding
  ENST00000444337 F7-004 113105839-113116788 nonsense_mediated_decay
  ENST00000473085 F7-005 113110679-113114903 processed_transcript
  ENST00000479674 F7-003 113110340-113116835 retained_intron
  ENST00000541084 F7-201 113105788-113120678 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungOvaryPlacentaTestisENST00000346342ENST00000444337ENST00000473085ENST00000541084
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Ovary Placenta Testis
ENST00000346342 0.206±0.00 0.197±0.00 N/A 0.248±0.06 0.074±0.01 0.028±0.00 0.034±0.01 31.529±0.00 58.651±0.00 0.039±0.00 1.027±1.39 0.181±0.12 1.016±0.08
ENST00000444337 N/A N/A 0.112±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000473085 N/A N/A N/A N/A N/A N/A N/A 0.107±0.00 N/A N/A N/A N/A N/A
ENST00000541084 N/A N/A 0.085±0.00 N/A N/A N/A N/A N/A N/A N/A 0.518±0.00 0.074±0.00 0.533±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0000RV CIL_0000RV_0001 CGP 13:112894378-113120681
CIL_00017F CIL_00017F_0001 CGP 13:113105788-113149529

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001948 IPI glycoprotein binding
GO:0002690 IDA positive regulation of leukocyte chemotaxis
GO:0003824 IEA catalytic activity
GO:0004175 IEA endopeptidase activity
GO:0004252 IEA serine-type endopeptidase activity
GO:0005102 IEA receptor binding
GO:0005509 IEA calcium ion binding
GO:0005515 IPI:IEA protein binding
GO:0005576 TAS:IEA extracellular region
GO:0005615 IEA extracellular space
GO:0005788 TAS endoplasmic reticulum lumen
GO:0005796 TAS Golgi lumen
GO:0005886 TAS plasma membrane
GO:0006508 TAS:IEA proteolysis
GO:0007596 TAS:IEA blood coagulation
GO:0007598 TAS blood coagulation, extrinsic pathway
GO:0007623 IEA circadian rhythm
GO:0008236 TAS serine-type peptidase activity
GO:0009725 IEA response to hormone
GO:0010641 IDA positive regulation of platelet-derived growth factor receptor signaling pathway
GO:0014070 IEA response to organic cyclic compound
GO:0017187 TAS peptidyl-glutamic acid carboxylation
GO:0030194 IEA positive regulation of blood coagulation
GO:0030335 TAS positive regulation of cell migration
GO:0031100 IEA organ regeneration
GO:0031667 IEA response to nutrient levels
GO:0031982 IEA vesicle
GO:0032571 IEA response to vitamin K
GO:0043627 IEA response to estrogen
GO:0043687 TAS post-translational protein modification
GO:0044267 TAS cellular protein metabolic process
GO:0050927 IDA positive regulation of positive chemotaxis
GO:0051897 IDA positive regulation of protein kinase B signaling
GO:0060416 IEA response to growth hormone

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000076045 F7 coagulation factor VII (serum prothrombin conversion accelerator) protein_coding Danio_rerio
ENSMUSG00000031443 F7 coagulation factor VII protein_coding Mus_musculus

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