C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: calcium/calmodulin-dependent protein kinase II beta
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000058404 CAMK2B 9606 - 7:44217150-44334577 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000258682 CAMK2B-026 44219430-44325424 protein_coding
  ENST00000346990 CAMK2B-007 44219430-44325424 protein_coding
  ENST00000347193 CAMK2B-005 44219430-44325424 protein_coding
  ENST00000350811 CAMK2B-008 44217150-44325496 protein_coding
  ENST00000353185 CAMK2B-009 44219417-44325485 nonsense_mediated_decay
  ENST00000353625 CAMK2B-006 44219351-44325431 protein_coding
  ENST00000358707 CAMK2B-004 44219346-44325625 protein_coding
  ENST00000395747 CAMK2B-003 44220062-44325421 protein_coding
  ENST00000395749 CAMK2B-002 44217156-44325498 protein_coding
  ENST00000415369 CAMK2B-016 44243470-44323962 protein_coding
  ENST00000421607 CAMK2B-020 44244889-44325447 protein_coding
  ENST00000424197 CAMK2B-015 44243473-44325474 protein_coding
  ENST00000425809 CAMK2B-022 44219213-44225913 protein_coding
  ENST00000427209 CAMK2B-024 44263005-44325519 processed_transcript
  ENST00000433930 CAMK2B-021 44225835-44242306 protein_coding
  ENST00000440254 CAMK2B-001 44219292-44325656 protein_coding
  ENST00000457475 CAMK2B-201 44217150-44325631 protein_coding
  ENST00000462128 CAMK2B-018 44247120-44268132 processed_transcript
  ENST00000466584 CAMK2B-023 44219349-44220953 retained_intron
  ENST00000470984 CAMK2B-013 44247129-44326167 processed_transcript
  ENST00000484972 CAMK2B-017 44243485-44268825 processed_transcript
  ENST00000489429 CAMK2B-011 44219365-44230347 processed_transcript
  ENST00000495819 CAMK2B-014 44243456-44325190 processed_transcript
  ENST00000497127 CAMK2B-019 44243251-44259581 processed_transcript
  ENST00000497584 CAMK2B-012 44219351-44334577 processed_transcript
  ENST00000523845 CAMK2B-027 44217559-44325475 nonsense_mediated_decay

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainColonHeartKidneyLiverMuscleOvaryPlacentaTestisENST00000258682ENST00000350811ENST00000353625ENST00000358707ENST00000395747ENST00000395749ENST00000425809ENST00000440254ENST00000457475ENST00000466584ENST00000495819
Transcript ID Adipose Adrenal Bladder Brain Colon Heart Kidney Liver Muscle Ovary Placenta Testis
ENST00000258682 N/A N/A N/A N/A N/A 2.749±0.00 N/A N/A N/A N/A N/A N/A
ENST00000350811 N/A N/A N/A 22.139±13.77 N/A N/A N/A N/A 4.377±0.00 N/A N/A N/A
ENST00000353625 N/A N/A N/A N/A N/A N/A N/A 0.078±0.00 N/A N/A N/A N/A
ENST00000358707 N/A N/A 0.098±0.00 N/A N/A N/A 0.748±0.00 N/A N/A 0.105±0.00 N/A 0.694±0.00
ENST00000395747 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.507±0.00
ENST00000395749 0.040±0.00 0.317±0.00 N/A N/A N/A 7.377±6.31 0.089±0.00 N/A 20.772±20.09 0.102±0.00 N/A 0.360±0.00
ENST00000425809 N/A N/A N/A N/A N/A N/A N/A 0.607±0.00 N/A 0.076±0.00 N/A N/A
ENST00000440254 N/A N/A N/A 13.705±0.00 N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000457475 N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.054±0.03 0.021±0.00 1.868±1.70
ENST00000466584 N/A N/A N/A N/A 0.485±0.00 N/A N/A N/A N/A 0.248±0.08 N/A N/A
ENST00000495819 N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.380±0.00 N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0000J6 CIL_0000J6_0001 CGP 7:44200968-44334577
CIL_0007BR CIL_0007BR_0002 CGP 7:44217150-44490880

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000082 IEA G1/S transition of mitotic cell cycle
GO:0002030 IEA inhibitory G-protein coupled receptor phosphorylation
GO:0003779 IEA actin binding
GO:0004672 IEA protein kinase activity
GO:0004674 IEA protein serine/threonine kinase activity
GO:0004683 IEA calmodulin-dependent protein kinase activity
GO:0004713 IEA protein tyrosine kinase activity
GO:0005516 IEA calmodulin binding
GO:0005524 IEA ATP binding
GO:0005654 TAS nucleoplasm
GO:0005829 TAS cytosol
GO:0005886 TAS plasma membrane
GO:0006468 TAS:IEA protein phosphorylation
GO:0006816 IEA calcium ion transport
GO:0007165 TAS signal transduction
GO:0007268 TAS synaptic transmission
GO:0010976 ISS positive regulation of neuron projection development
GO:0014733 TAS regulation of skeletal muscle adaptation
GO:0016529 IEA sarcoplasmic reticulum
GO:0016772 IEA transferase activity, transferring phosphorus-containing groups
GO:0018105 IEA peptidyl-serine phosphorylation
GO:0019221 TAS cytokine-mediated signaling pathway
GO:0030666 TAS endocytic vesicle membrane
GO:0032222 IEA regulation of synaptic transmission, cholinergic
GO:0042803 IPI protein homodimerization activity
GO:0046686 IEA response to cadmium ion
GO:0046777 IDA protein autophosphorylation
GO:0048169 TAS regulation of long-term neuronal synaptic plasticity
GO:0050885 IEA neuromuscular process controlling balance
GO:0051233 IEA spindle midzone
GO:0051823 TAS regulation of synapse structural plasticity
GO:0051924 TAS regulation of calcium ion transport
GO:0060333 TAS interferon-gamma-mediated signaling pathway
GO:0060466 IEA activation of meiosis involved in egg activation
GO:0060998 TAS regulation of dendritic spine development
GO:0061003 ISS positive regulation of dendritic spine morphogenesis
GO:0090129 ISS positive regulation of synapse maturation
GO:2001235 IEA positive regulation of apoptotic signaling pathway

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000011065 camk2b1 calcium/calmodulin-dependent protein kinase (CaM kinase) II beta 1 protein_coding Danio_rerio
ENSDARG00000021065 camk2b2 calcium/calmodulin-dependent protein kinase (CaM kinase) II beta 2 protein_coding Danio_rerio
ENSMUSG00000057897 Camk2b calcium/calmodulin-dependent protein kinase II, beta protein_coding Mus_musculus

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