C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: calcium/calmodulin-dependent protein kinase II, beta
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000057897 Camk2b 10090 - 11:5969644-6066362 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000002817 Camk2b-008 5971672-6065742 protein_coding
  ENSMUST00000019133 Camk2b-009 5971680-6065612 protein_coding
  ENSMUST00000066431 Camk2b-001 5971672-6065545 protein_coding
  ENSMUST00000090443 Camk2b-201 5969672-6065748 protein_coding
  ENSMUST00000093355 Camk2b-002 5971669-6065582 protein_coding
  ENSMUST00000101585 Camk2b-004 5971735-6065538 protein_coding
  ENSMUST00000101586 Camk2b-011 5972217-6065570 protein_coding
  ENSMUST00000109812 Camk2b-010 5971568-6065563 protein_coding
  ENSMUST00000109813 Camk2b-003 5969644-6065748 protein_coding
  ENSMUST00000109815 Camk2b-202 5969672-6065563 protein_coding
  ENSMUST00000123391 Camk2b-007 5992820-6066362 processed_transcript
  ENSMUST00000129098 Camk2b-006 6011665-6065658 processed_transcript
  ENSMUST00000130427 Camk2b-012 5990395-6000448 processed_transcript
  ENSMUST00000154197 Camk2b-005 5988101-6065538 processed_transcript
  ENSMUST00000155755 Camk2b-013 5969668-5984138 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000002817ENSMUST00000019133ENSMUST00000066431ENSMUST00000090443ENSMUST00000093355ENSMUST00000101586ENSMUST00000109812ENSMUST00000109813ENSMUST00000109815ENSMUST00000129098ENSMUST00000155755
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000002817 N/A 3.069±1.38 0.460±0.00 23.013±2.48 N/A 3.118±0.16 N/A N/A 0.207±0.00 1.770±0.00 N/A 0.868±0.35 0.143±0.00 0.511±0.02
ENSMUST00000019133 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 14.432±0.00 N/A N/A N/A
ENSMUST00000066431 1.044±0.00 N/A N/A N/A 1.217±0.42 6.162±0.74 N/A N/A 0.954±0.25 N/A N/A 1.560±0.29 N/A 0.801±0.17
ENSMUST00000090443 0.451±0.00 1.227±0.38 0.172±0.00 N/A N/A 2.141±0.48 0.835±0.00 0.407±0.06 0.290±0.18 0.860±0.00 N/A 0.400±0.00 N/A N/A
ENSMUST00000093355 N/A N/A N/A N/A 0.479±0.00 N/A N/A N/A N/A N/A N/A N/A 0.085±0.00 N/A
ENSMUST00000101586 N/A N/A N/A N/A 2.260±0.00 N/A N/A N/A 0.515±0.00 N/A N/A N/A N/A N/A
ENSMUST00000109812 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.387±0.00
ENSMUST00000109813 N/A 2.008±0.57 0.208±0.04 13.522±2.84 4.142±2.54 N/A 1.415±0.52 0.809±0.09 0.063±0.00 N/A 11.317±2.70 0.445±0.22 0.037±0.00 N/A
ENSMUST00000109815 N/A N/A N/A 317.752±0.00 N/A N/A N/A N/A 0.623±0.39 N/A N/A N/A N/A N/A
ENSMUST00000129098 N/A N/A N/A N/A 0.242±0.00 N/A N/A 0.282±0.02 N/A N/A N/A 0.368±0.11 N/A N/A
ENSMUST00000155755 N/A 4.140±0.82 0.515±0.24 N/A 0.644±0.22 6.880±2.44 N/A N/A 0.143±0.00 N/A N/A 0.634±0.11 0.049±0.00 0.619±0.28

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0000J6 CIL_0000J6_0002 CGP 11:5955693-6066362
CIL_0007BR CIL_0007BR_0003 CGP 11:5969644-6200415

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000082 IMP G1/S transition of mitotic cell cycle
GO:0002030 IDA inhibitory G-protein coupled receptor phosphorylation
GO:0004674 IMP protein serine/threonine kinase activity
GO:0004683 IDA calmodulin-dependent protein kinase activity
GO:0005515 IPI protein binding
GO:0005516 IEA calmodulin binding
GO:0005524 IEA ATP binding
GO:0005829 IDA cytosol
GO:0005954 TAS calcium- and calmodulin-dependent protein kinase complex
GO:0006816 IMP calcium ion transport
GO:0010976 ISS positive regulation of neuron projection development
GO:0016020 IEA membrane
GO:0016529 IEA sarcoplasmic reticulum
GO:0018105 IDA peptidyl-serine phosphorylation
GO:0032222 IMP regulation of synaptic transmission, cholinergic
GO:0042803 IEA protein homodimerization activity
GO:0046686 IDA response to cadmium ion
GO:0046777 IMP protein autophosphorylation
GO:0048169 IMP regulation of long-term neuronal synaptic plasticity
GO:0050885 IMP neuromuscular process controlling balance
GO:0051233 IDA spindle midzone
GO:0060466 IMP activation of meiosis involved in egg activation
GO:0061003 ISS positive regulation of dendritic spine morphogenesis
GO:0090129 ISS positive regulation of synapse maturation
GO:2001235 IDA positive regulation of apoptotic signaling pathway

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000011065 camk2b1 calcium/calmodulin-dependent protein kinase (CaM kinase) II beta 1 protein_coding Danio_rerio
ENSDARG00000021065 camk2b2 calcium/calmodulin-dependent protein kinase (CaM kinase) II beta 2 protein_coding Danio_rerio
ENSG00000058404 CAMK2B calcium/calmodulin-dependent protein kinase II beta protein_coding Homo_sapiens

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