C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: protein tyrosine phosphatase, receptor type, U
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000060656 PTPRU 9606 + 1:29236516-29326813 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000345512 PTPRU-003 29236516-29325661 protein_coding
  ENST00000373779 PTPRU-001 29236516-29326800 protein_coding
  ENST00000415600 PTPRU-006 29279551-29312706 processed_transcript
  ENST00000428026 PTPRU-008 29236549-29326813 protein_coding
  ENST00000460170 PTPRU-002 29236639-29326669 protein_coding
  ENST00000465525 PTPRU-004 29320210-29326212 retained_intron
  ENST00000492954 PTPRU-005 29323218-29325650 retained_intron
  ENST00000493601 PTPRU-007 29317760-29325298 processed_transcript
  ENST00000526080 PTPRU-011 29311346-29312659 retained_intron
  ENST00000527027 PTPRU-009 29260181-29275685 processed_transcript
  ENST00000531385 PTPRU-010 29283723-29304040 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000345512ENST00000373779ENST00000415600ENST00000428026ENST00000460170ENST00000492954ENST00000531385
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000345512 N/A N/A 0.235±0.00 N/A N/A N/A N/A 0.624±0.00 N/A N/A N/A N/A N/A N/A
ENST00000373779 3.206±0.00 N/A N/A N/A 6.705±0.00 2.582±0.00 2.622±0.00 0.761±0.00 1.219±0.13 2.854±1.10 3.853±0.00 5.986±4.74 7.946±1.62 0.998±0.41
ENST00000415600 N/A N/A N/A N/A N/A N/A N/A 0.390±0.00 N/A N/A 0.858±0.00 N/A N/A N/A
ENST00000428026 1.204±0.00 0.596±0.00 N/A N/A N/A N/A N/A 0.949±0.00 N/A N/A 7.849±0.00 3.536±1.38 2.127±0.00 2.591±0.00
ENST00000460170 N/A N/A N/A 2.886±0.00 0.533±0.00 N/A 1.765±0.00 N/A N/A N/A 5.311±0.00 N/A N/A N/A
ENST00000492954 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 5.172±0.00 N/A N/A N/A
ENST00000531385 N/A N/A 0.513±0.00 N/A N/A N/A 1.245±0.00 N/A N/A N/A 2.776±0.00 N/A N/A N/A

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004725 IDA:IEA protein tyrosine phosphatase activity
GO:0005001 NAS transmembrane receptor protein tyrosine phosphatase activity
GO:0005515 IPI:IEA protein binding
GO:0005886 TAS plasma membrane
GO:0005887 NAS integral component of plasma membrane
GO:0005911 IDA cell-cell junction
GO:0006470 IDA:IEA protein dephosphorylation
GO:0007155 NAS cell adhesion
GO:0007185 NAS transmembrane receptor protein tyrosine phosphatase signaling pathway
GO:0008013 IPI beta-catenin binding
GO:0008285 IDA negative regulation of cell proliferation
GO:0016020 IEA membrane
GO:0016311 IEA dephosphorylation
GO:0016337 IDA single organismal cell-cell adhesion
GO:0016791 IEA phosphatase activity
GO:0030154 IEA cell differentiation
GO:0030336 IDA negative regulation of cell migration
GO:0031100 IEA organ regeneration
GO:0034109 IEA homotypic cell-cell adhesion
GO:0034394 IDA protein localization to cell surface
GO:0035335 IEA peptidyl-tyrosine dephosphorylation
GO:0051384 IEA response to glucocorticoid
GO:0060070 IDA canonical Wnt signaling pathway

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000078090 ptprub protein tyrosine phosphatase, receptor type, U, b protein_coding Danio_rerio
ENSDARG00000092638 ptprua protein tyrosine phosphatase, receptor type, U, a protein_coding Danio_rerio
ENSDARG00000094911 PTPRU (3 of 3) protein tyrosine phosphatase, receptor type, U protein_coding Danio_rerio
ENSMUSG00000028909 Ptpru protein tyrosine phosphatase, receptor type, U protein_coding Mus_musculus

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