C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: polymerase (DNA directed), delta 1, catalytic subunit
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000062822 POLD1 9606 + 19:50384204-50418018 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000440232 POLD1-002 50384339-50418014 protein_coding
  ENST00000593407 POLD1-008 50413503-50417063 protein_coding
  ENST00000593887 POLD1-012 50384373-50399484 protein_coding
  ENST00000593981 POLD1-011 50413866-50417923 protein_coding
  ENST00000595904 POLD1-004 50398852-50417947 protein_coding
  ENST00000596221 POLD1-006 50416953-50418010 retained_intron
  ENST00000596425 POLD1-009 50407084-50413501 protein_coding
  ENST00000596648 POLD1-010 50415509-50417091 retained_intron
  ENST00000597963 POLD1-007 50416313-50418016 retained_intron
  ENST00000599857 POLD1-001 50384351-50418014 protein_coding
  ENST00000600746 POLD1-005 50384367-50402665 retained_intron
  ENST00000600859 POLD1-003 50384204-50418012 nonsense_mediated_decay
  ENST00000601098 POLD1-013 50384342-50402142 protein_coding
  ENST00000613923 POLD1-201 50384323-50418018 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000440232ENST00000593407ENST00000595904ENST00000596221ENST00000596425ENST00000599857ENST00000600746ENST00000600859ENST00000601098ENST00000613923
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000440232 3.189±0.00 5.900±0.00 N/A 0.311±0.21 1.340±0.98 1.574±1.19 0.715±0.59 1.973±1.34 0.946±0.25 3.503±2.82 3.337±0.00 6.864±3.39 6.276±2.04 8.088±0.00
ENST00000593407 N/A N/A N/A N/A 5.156±0.00 N/A N/A 4.358±0.00 0.986±0.36 N/A 4.729±0.00 N/A N/A 11.993±0.00
ENST00000595904 N/A N/A N/A N/A N/A N/A 0.348±0.00 N/A N/A N/A N/A 5.959±0.00 7.353±0.00 11.460±0.00
ENST00000596221 N/A N/A N/A 0.461±0.00 N/A N/A N/A N/A N/A N/A N/A 10.652±0.00 N/A 18.873±0.00
ENST00000596425 N/A N/A N/A 0.188±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000599857 N/A N/A N/A 0.444±0.00 0.524±0.00 N/A N/A N/A N/A N/A N/A N/A 2.337±0.00 N/A
ENST00000600746 N/A N/A 0.091±0.00 0.306±0.00 N/A 1.534±0.00 0.847±0.00 N/A 0.748±0.00 2.387±0.00 1.535±0.00 1.502±0.00 N/A N/A
ENST00000600859 N/A N/A N/A N/A 1.399±0.00 N/A N/A N/A N/A N/A N/A 0.216±0.00 N/A N/A
ENST00000601098 N/A N/A N/A N/A 1.487±0.00 1.415±0.00 N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000613923 N/A N/A N/A N/A N/A N/A 0.366±0.00 N/A N/A N/A N/A N/A N/A N/A

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000109 IDA nucleotide-excision repair complex
GO:0000166 IEA nucleotide binding
GO:0000278 TAS mitotic cell cycle
GO:0000722 TAS telomere maintenance via recombination
GO:0000723 TAS telomere maintenance
GO:0000731 IMP DNA synthesis involved in DNA repair
GO:0003676 IEA nucleic acid binding
GO:0003677 IDA:IEA DNA binding
GO:0003682 IDA chromatin binding
GO:0003887 IMP:IEA DNA-directed DNA polymerase activity
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005654 TAS nucleoplasm
GO:0005737 IDA cytoplasm
GO:0006260 IMP DNA replication
GO:0006271 TAS DNA strand elongation involved in DNA replication
GO:0006281 TAS DNA repair
GO:0006283 TAS transcription-coupled nucleotide-excision repair
GO:0006284 TAS base-excision repair
GO:0006287 IDA base-excision repair, gap-filling
GO:0006289 TAS nucleotide-excision repair
GO:0006297 IMP nucleotide-excision repair, DNA gap filling
GO:0007346 IBA regulation of mitotic cell cycle
GO:0008408 IBA 3'-5' exonuclease activity
GO:0009411 TAS response to UV
GO:0016020 IDA membrane
GO:0016235 IDA aggresome
GO:0032201 TAS telomere maintenance via semi-conservative replication
GO:0043137 IBA DNA replication, removal of RNA primer
GO:0043625 IBA delta DNA polymerase complex
GO:0044281 TAS small molecule metabolic process
GO:0045004 IBA DNA replication proofreading
GO:0046872 IEA metal ion binding
GO:0051539 IEA 4 iron, 4 sulfur cluster binding
GO:0055089 IMP fatty acid homeostasis
GO:0071897 IEA DNA biosynthetic process

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000027689 pold1 polymerase (DNA directed), delta 1, catalytic subunit protein_coding Danio_rerio
ENSMUSG00000038644 Pold1 polymerase (DNA directed), delta 1, catalytic subunit protein_coding Mus_musculus

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