C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: EYA transcriptional coactivator and phosphatase 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000064655 EYA2 9606 + 20:46894624-47188844 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000317304 EYA2-009 46990001-47188136 protein_coding
  ENST00000327619 EYA2-005 46894624-47188844 protein_coding
  ENST00000357410 EYA2-008 46894624-47188844 protein_coding
  ENST00000458636 EYA2-004 47001460-47143149 protein_coding
  ENST00000471081 EYA2-002 46979692-46990025 processed_transcript
  ENST00000475856 EYA2-006 47089239-47096080 processed_transcript
  ENST00000479843 EYA2-001 46979483-46990025 processed_transcript
  ENST00000497062 EYA2-003 46894870-47188844 protein_coding
  ENST00000497428 EYA2-007 46978235-46990070 processed_transcript
  ENST00000611592 EYA2-201 46894624-47188844 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000317304ENST00000327619ENST00000357410ENST00000458636ENST00000475856ENST00000497062ENST00000497428ENST00000611592
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000317304 N/A N/A 0.903±0.00 N/A 0.720±0.00 0.422±0.00 N/A 0.072±0.00 0.351±0.00 N/A 0.420±0.00 0.084±0.00 N/A N/A
ENST00000327619 N/A N/A N/A N/A N/A 0.648±0.05 N/A 1.882±0.00 N/A 3.107±0.00 N/A 0.728±0.02 4.174±1.81 N/A
ENST00000357410 0.712±0.00 1.181±0.00 N/A N/A N/A 1.591±0.00 0.106±0.06 N/A N/A 1.203±0.00 N/A N/A N/A N/A
ENST00000458636 N/A N/A 3.247±0.00 1.126±0.00 N/A N/A 0.092±0.00 N/A 0.548±0.00 1.792±0.00 N/A N/A N/A N/A
ENST00000475856 N/A N/A 1.024±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000497062 1.273±0.00 1.619±0.00 N/A 0.837±0.11 1.148±0.68 2.847±0.00 N/A 1.249±0.00 0.097±0.05 N/A N/A 0.999±0.79 5.130±3.60 3.356±0.72
ENST00000497428 N/A N/A N/A N/A N/A N/A 0.265±0.00 N/A N/A N/A N/A N/A N/A N/A
ENST00000611592 0.939±0.00 0.510±0.00 N/A 2.359±0.00 5.889±0.00 1.265±0.00 0.517±0.00 1.180±0.00 0.300±0.06 N/A 0.859±0.00 1.075±0.00 2.923±0.00 5.549±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0001XY CIL_0001XY_0001 CGP 20:46709487-47188844
CIL_0004DE CIL_0004DE_0001 CGP 20:46894624-47356889

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000287 IDA magnesium ion binding
GO:0004725 IEA protein tyrosine phosphatase activity
GO:0005515 IPI protein binding
GO:0005634 IEA nucleus
GO:0005737 IDA cytoplasm
GO:0005739 IEA mitochondrion
GO:0005813 IDA centrosome
GO:0006281 IEA DNA repair
GO:0006351 IEA transcription, DNA-templated
GO:0006355 IEA regulation of transcription, DNA-templated
GO:0006470 IEA protein dephosphorylation
GO:0007275 IEA multicellular organismal development
GO:0007501 TAS mesodermal cell fate specification
GO:0014706 IEA striated muscle tissue development
GO:0016576 IDA histone dephosphorylation
GO:0035335 IEA peptidyl-tyrosine dephosphorylation
GO:0097192 IEA extrinsic apoptotic signaling pathway in absence of ligand
GO:0097345 IEA mitochondrial outer membrane permeabilization

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000018984 eya2 eyes absent homolog 2 (Drosophila) protein_coding Danio_rerio
ENSMUSG00000017897 Eya2 eyes absent 2 homolog (Drosophila) protein_coding Mus_musculus

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