C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: eyes absent 2 homolog (Drosophila)
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000017897 Eya2 10090 + 2:165595032-165771727 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000063433 Eya2-001 165655298-165771727 protein_coding
  ENSMUST00000088132 Eya2-201 165595032-165771719 protein_coding
  ENSMUST00000128280 Eya2-005 165769186-165771262 processed_transcript
  ENSMUST00000128696 Eya2-002 165761824-165767129 processed_transcript
  ENSMUST00000150638 Eya2-004 165713569-165766260 processed_transcript
  ENSMUST00000150669 Eya2-003 165655318-165716069 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000063433ENSMUST00000088132ENSMUST00000128280ENSMUST00000128696ENSMUST00000150638ENSMUST00000150669
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000063433 3.231±1.86 1.285±0.09 2.094±0.40 N/A 5.385±2.86 0.499±0.24 0.297±0.05 0.268±0.00 0.049±0.01 N/A N/A 6.657±3.21 0.037±0.00 N/A
ENSMUST00000088132 8.264±5.76 1.417±0.54 2.387±0.36 2.171±1.45 3.440±1.53 0.533±0.26 1.100±0.46 2.213±0.42 0.062±0.03 23.976±4.34 0.665±0.10 18.999±10.66 0.187±0.08 0.414±0.24
ENSMUST00000128280 N/A N/A N/A N/A N/A N/A N/A N/A 0.357±0.04 N/A N/A N/A N/A N/A
ENSMUST00000128696 N/A N/A N/A N/A N/A 1.714±0.00 N/A N/A 0.104±0.00 N/A N/A N/A 0.155±0.00 N/A
ENSMUST00000150638 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.295±0.00 N/A N/A 0.028±0.00
ENSMUST00000150669 N/A N/A N/A N/A N/A 0.266±0.00 N/A N/A 0.084±0.04 N/A N/A N/A 0.108±0.00 N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0001XY CIL_0001XY_0002 CGP 2:165503787-165771727
CIL_0004DE CIL_0004DE_0002 CGP 2:165595032-165899016

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000287 ISS magnesium ion binding
GO:0004725 ISS protein tyrosine phosphatase activity
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005737 IDA cytoplasm
GO:0005739 IDA mitochondrion
GO:0005813 IEA centrosome
GO:0006281 IEA DNA repair
GO:0006351 IEA transcription, DNA-templated
GO:0006355 IEA regulation of transcription, DNA-templated
GO:0006470 IDA protein dephosphorylation
GO:0007275 IEA multicellular organismal development
GO:0014706 IGI striated muscle tissue development
GO:0016576 ISS histone dephosphorylation
GO:0035335 IEA peptidyl-tyrosine dephosphorylation
GO:0097192 IDA extrinsic apoptotic signaling pathway in absence of ligand
GO:0097345 IDA mitochondrial outer membrane permeabilization

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000018984 eya2 eyes absent homolog 2 (Drosophila) protein_coding Danio_rerio
ENSG00000064655 EYA2 EYA transcriptional coactivator and phosphatase 2 protein_coding Homo_sapiens

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