C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: B-cell CLL/lymphoma 3
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000069399 BCL3 9606 + 19:44747705-44760044 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000164227 BCL3-001 44748547-44760044 protein_coding
  ENST00000403534 BCL3-003 44747705-44759486 retained_intron
  ENST00000444487 BCL3-005 44751321-44759463 protein_coding
  ENST00000464319 BCL3-007 44756145-44757364 retained_intron
  ENST00000473468 BCL3-004 44755149-44757168 processed_transcript
  ENST00000473473 BCL3-008 44758528-44759558 retained_intron
  ENST00000474300 BCL3-006 44757589-44759825 retained_intron
  ENST00000477832 BCL3-009 44757657-44758563 retained_intron
  ENST00000487394 BCL3-002 44747836-44749004 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000164227ENST00000403534ENST00000444487ENST00000473468ENST00000473473ENST00000474300ENST00000477832ENST00000487394
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000164227 8.119±0.00 28.548±0.00 0.047±0.00 2.145±0.00 4.005±3.53 9.915±8.78 4.611±4.59 8.301±8.13 18.335±17.51 154.551±0.00 12.027±0.00 37.252±39.18 8.503±1.73 6.281±2.92
ENST00000403534 N/A N/A 0.038±0.00 N/A N/A N/A N/A N/A 0.399±0.00 N/A N/A N/A N/A N/A
ENST00000444487 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.328±0.00 N/A N/A N/A
ENST00000473468 N/A N/A N/A N/A N/A 1.904±0.00 N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000473473 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 6.769±0.00 N/A N/A
ENST00000474300 9.676±0.00 50.957±0.00 N/A 0.773±0.00 8.509±0.00 17.733±0.00 N/A 7.904±0.00 N/A N/A N/A 0.964±0.00 N/A 11.050±0.00
ENST00000477832 N/A N/A N/A N/A 2.121±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000487394 N/A N/A N/A N/A 1.059±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00044F CIL_00044F_0002 CGP 19:44747705-44800634

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000060 IMP protein import into nucleus, translocation
GO:0002268 IEA follicular dendritic cell differentiation
GO:0002315 IEA marginal zone B cell differentiation
GO:0002455 IEA humoral immune response mediated by circulating immunoglobulin
GO:0002467 IEA germinal center formation
GO:0003677 IEA DNA binding
GO:0003700 IEA sequence-specific DNA binding transcription factor activity
GO:0005515 IPI:IEA protein binding
GO:0005634 IDA nucleus
GO:0005737 IDA cytoplasm
GO:0006351 IDA transcription, DNA-templated
GO:0006974 IDA cellular response to DNA damage stimulus
GO:0007249 IDA I-kappaB kinase/NF-kappaB signaling
GO:0008134 IPI transcription factor binding
GO:0009615 IDA response to virus
GO:0010225 IDA response to UV-C
GO:0019730 IEA antimicrobial humoral response
GO:0030198 IEA extracellular matrix organization
GO:0030330 IMP DNA damage response, signal transduction by p53 class mediator
GO:0030674 TAS protein binding, bridging
GO:0032729 IEA positive regulation of interferon-gamma production
GO:0032996 IDA Bcl3-Bcl10 complex
GO:0033257 IDA Bcl3/NF-kappaB2 complex
GO:0042088 IEA T-helper 1 type immune response
GO:0042345 IEP regulation of NF-kappaB import into nucleus
GO:0042536 IEA negative regulation of tumor necrosis factor biosynthetic process
GO:0042742 IEA defense response to bacterium
GO:0042771 IMP intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
GO:0042832 IEA defense response to protozoan
GO:0042981 IDA regulation of apoptotic process
GO:0043066 IDA negative regulation of apoptotic process
GO:0043234 IDA protein complex
GO:0045064 IEA T-helper 2 cell differentiation
GO:0045082 IEA positive regulation of interleukin-10 biosynthetic process
GO:0045171 IDA intercellular bridge
GO:0045415 IMP negative regulation of interleukin-8 biosynthetic process
GO:0045727 IMP positive regulation of translation
GO:0045892 IDA negative regulation of transcription, DNA-templated
GO:0045893 IDA positive regulation of transcription, DNA-templated
GO:0045944 IEA positive regulation of transcription from RNA polymerase II promoter
GO:0048536 IEA spleen development
GO:0051101 IEP regulation of DNA binding
GO:0051457 NAS maintenance of protein location in nucleus

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000087832 bcl3 B-cell CLL/lymphoma 3 protein_coding Danio_rerio
ENSMUSG00000053175 Bcl3 B cell leukemia/lymphoma 3 protein_coding Mus_musculus

Loading