C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: B-cell CLL/lymphoma 3
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000164227 BCL3-001 ENSG00000069399 9606 + 19:44748547-44760044 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000164227
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000164227 8.119±0.00 28.548±0.00 0.047±0.00 2.145±0.00 4.005±3.53 9.915±8.78 4.611±4.59 8.301±8.13 18.335±17.51 154.551±0.00 12.027±0.00 37.252±39.18 8.503±1.73 6.281±2.92

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00044F CIL_00044F_0002 CGP 19:44747705-44800634

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000060 IMP protein import into nucleus, translocation
GO:0002268 IEA follicular dendritic cell differentiation
GO:0002315 IEA marginal zone B cell differentiation
GO:0002455 IEA humoral immune response mediated by circulating immunoglobulin
GO:0002467 IEA germinal center formation
GO:0003677 IEA DNA binding
GO:0003700 IEA sequence-specific DNA binding transcription factor activity
GO:0005515 IPI:IEA protein binding
GO:0005634 IDA nucleus
GO:0005737 IDA cytoplasm
GO:0006351 IDA transcription, DNA-templated
GO:0006974 IDA cellular response to DNA damage stimulus
GO:0007249 IDA I-kappaB kinase/NF-kappaB signaling
GO:0008134 IPI transcription factor binding
GO:0009615 IDA response to virus
GO:0010225 IDA response to UV-C
GO:0019730 IEA antimicrobial humoral response
GO:0030198 IEA extracellular matrix organization
GO:0030330 IMP DNA damage response, signal transduction by p53 class mediator
GO:0030674 TAS protein binding, bridging
GO:0032729 IEA positive regulation of interferon-gamma production
GO:0032996 IDA Bcl3-Bcl10 complex
GO:0033257 IDA Bcl3/NF-kappaB2 complex
GO:0042088 IEA T-helper 1 type immune response
GO:0042345 IEP regulation of NF-kappaB import into nucleus
GO:0042536 IEA negative regulation of tumor necrosis factor biosynthetic process
GO:0042742 IEA defense response to bacterium
GO:0042771 IMP intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
GO:0042832 IEA defense response to protozoan
GO:0042981 IDA regulation of apoptotic process
GO:0043066 IDA negative regulation of apoptotic process
GO:0043234 IDA protein complex
GO:0045064 IEA T-helper 2 cell differentiation
GO:0045082 IEA positive regulation of interleukin-10 biosynthetic process
GO:0045171 IDA intercellular bridge
GO:0045415 IMP negative regulation of interleukin-8 biosynthetic process
GO:0045727 IMP positive regulation of translation
GO:0045892 IDA negative regulation of transcription, DNA-templated
GO:0045893 IDA positive regulation of transcription, DNA-templated
GO:0045944 IEA positive regulation of transcription from RNA polymerase II promoter
GO:0048536 IEA spleen development
GO:0051101 IEP regulation of DNA binding
GO:0051457 NAS maintenance of protein location in nucleus

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000120537 Bcl3-001 protein_coding Mus_musculus 0 1349
ENSMUST00000146194 Bcl3-006 processed_transcript Mus_musculus 0 424
ENSMUST00000135609 Bcl3-003 protein_coding Mus_musculus 0 379
ENSMUST00000123375 Bcl3-007 retained_intron Mus_musculus 0 316
ENSMUST00000152768 Bcl3-008 retained_intron Mus_musculus 0 311
ENSMUST00000139680 Bcl3-004 protein_coding Mus_musculus 0 289
ENSMUST00000141996 Bcl3-005 processed_transcript Mus_musculus 0 261

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