C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: B cell leukemia/lymphoma 3
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000053175 Bcl3 10090 - 7:19808462-19822770 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000120537 Bcl3-001 19808462-19822770 protein_coding
  ENSMUST00000123375 Bcl3-007 19811349-19812833 retained_intron
  ENSMUST00000135609 Bcl3-003 19808462-19811121 protein_coding
  ENSMUST00000139680 Bcl3-004 19811586-19822157 protein_coding
  ENSMUST00000141996 Bcl3-005 19811495-19815996 processed_transcript
  ENSMUST00000146194 Bcl3-006 19812395-19822770 processed_transcript
  ENSMUST00000152768 Bcl3-008 19811117-19811889 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000120537ENSMUST00000123375ENSMUST00000135609ENSMUST00000139680ENSMUST00000141996ENSMUST00000146194
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000120537 5.439±0.52 15.690±0.90 4.906±0.45 0.152±0.07 26.932±6.56 30.980±1.33 2.990±1.11 3.463±0.74 9.072±6.48 9.433±2.05 0.657±0.43 9.185±3.09 2.544±1.48 1.004±0.16
ENSMUST00000123375 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.105±0.00 1.032±0.00 N/A N/A
ENSMUST00000135609 N/A N/A N/A 0.261±0.00 N/A N/A N/A N/A N/A N/A 0.328±0.00 N/A 2.573±2.19 N/A
ENSMUST00000139680 N/A N/A N/A 0.237±0.00 N/A N/A 2.447±0.28 N/A N/A N/A 0.234±0.00 7.017±0.05 1.451±0.00 N/A
ENSMUST00000141996 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 8.046±0.00 N/A
ENSMUST00000146194 7.501±0.08 45.292±9.12 N/A N/A 49.839±17.45 60.679±8.68 N/A 2.145±0.00 14.981±3.06 15.515±6.10 N/A 30.558±6.26 N/A N/A

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000060 IEA protein import into nucleus, translocation
GO:0002268 IMP follicular dendritic cell differentiation
GO:0002315 IMP marginal zone B cell differentiation
GO:0002455 IMP humoral immune response mediated by circulating immunoglobulin
GO:0002467 IMP germinal center formation
GO:0003677 IDA DNA binding
GO:0003700 IDA sequence-specific DNA binding transcription factor activity
GO:0005515 IPI protein binding
GO:0005634 IEA nucleus
GO:0005737 IEA cytoplasm
GO:0006351 IEA transcription, DNA-templated
GO:0006974 IEA cellular response to DNA damage stimulus
GO:0007249 IEA I-kappaB kinase/NF-kappaB signaling
GO:0008134 IEA transcription factor binding
GO:0009615 IEA response to virus
GO:0010225 IEA response to UV-C
GO:0019730 IMP antimicrobial humoral response
GO:0030198 IMP extracellular matrix organization
GO:0030330 IEA DNA damage response, signal transduction by p53 class mediator
GO:0032729 IMP positive regulation of interferon-gamma production
GO:0032996 IEA Bcl3-Bcl10 complex
GO:0033257 IEA Bcl3/NF-kappaB2 complex
GO:0042088 IMP T-helper 1 type immune response
GO:0042345 IEA regulation of NF-kappaB import into nucleus
GO:0042536 IMP negative regulation of tumor necrosis factor biosynthetic process
GO:0042742 IMP defense response to bacterium
GO:0042771 IEA intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
GO:0042832 IMP defense response to protozoan
GO:0042981 IEA regulation of apoptotic process
GO:0043066 IGI negative regulation of apoptotic process
GO:0043234 IEA protein complex
GO:0045064 IMP T-helper 2 cell differentiation
GO:0045082 IMP positive regulation of interleukin-10 biosynthetic process
GO:0045171 IEA intercellular bridge
GO:0045415 IEA negative regulation of interleukin-8 biosynthetic process
GO:0045727 IEA positive regulation of translation
GO:0045892 IEA negative regulation of transcription, DNA-templated
GO:0045893 IEA positive regulation of transcription, DNA-templated
GO:0045944 IDA positive regulation of transcription from RNA polymerase II promoter
GO:0048536 IMP spleen development
GO:0051101 IEA regulation of DNA binding

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000087832 bcl3 B-cell CLL/lymphoma 3 protein_coding Danio_rerio
ENSG00000069399 BCL3 B-cell CLL/lymphoma 3 protein_coding Homo_sapiens

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