C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: RAB27A, member RAS oncogene family
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000069974 RAB27A 9606 - 15:55202966-55319113 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000336787 RAB27A-201 55202969-55289815 protein_coding
  ENST00000396307 RAB27A-001 55202966-55270394 protein_coding
  ENST00000561545 RAB27A-011 55289888-55319110 processed_transcript
  ENST00000563262 RAB27A-009 55228666-55319113 protein_coding
  ENST00000564609 RAB27A-002 55205349-55270286 protein_coding
  ENST00000565776 RAB27A-007 55269794-55289791 retained_intron
  ENST00000565972 RAB27A-004 55223948-55270901 protein_coding
  ENST00000566877 RAB27A-006 55205616-55249035 protein_coding
  ENST00000567380 RAB27A-010 55223916-55270874 protein_coding
  ENST00000567639 RAB27A-008 55238118-55289813 retained_intron
  ENST00000568803 RAB27A-005 55230425-55270256 protein_coding
  ENST00000569493 RAB27A-003 55205353-55270909 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalColonKidneyLiverLungOvaryPlacentaTestisENST00000336787ENST00000396307
Transcript ID Adipose Adrenal Colon Kidney Liver Lung Ovary Placenta Testis
ENST00000336787 5.223±0.00 8.866±0.00 8.923±0.00 6.530±0.00 7.774±0.00 14.535±0.00 5.582±1.14 5.158±0.45 6.117±0.00
ENST00000396307 N/A N/A N/A N/A N/A 4.383±0.00 2.495±0.00 N/A N/A

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001750 IEA photoreceptor outer segment
GO:0003924 ISS:IEA GTPase activity
GO:0005515 IPI protein binding
GO:0005525 ISS:IEA GTP binding
GO:0005622 IEA intracellular
GO:0005764 IDA lysosome
GO:0005770 IDA late endosome
GO:0005794 IEA Golgi apparatus
GO:0006184 IEA GTP catabolic process
GO:0006605 IEA protein targeting
GO:0006886 IEA intracellular protein transport
GO:0006887 IDA exocytosis
GO:0006913 IEA nucleocytoplasmic transport
GO:0007165 IEA signal transduction
GO:0007264 IEA small GTPase mediated signal transduction
GO:0007596 IEA blood coagulation
GO:0010628 IMP positive regulation of gene expression
GO:0015031 IEA protein transport
GO:0016020 IEA membrane
GO:0016192 IEA vesicle-mediated transport
GO:0016324 IEA apical plasma membrane
GO:0019003 IDA GDP binding
GO:0019882 IMP antigen processing and presentation
GO:0019904 IEA protein domain specific binding
GO:0030141 IEA secretory granule
GO:0030318 IEA melanocyte differentiation
GO:0030425 IDA dendrite
GO:0030667 IEA secretory granule membrane
GO:0031489 IEA myosin V binding
GO:0032400 IEA melanosome localization
GO:0032402 IEA melanosome transport
GO:0032585 IDA multivesicular body membrane
GO:0036257 IMP multivesicular body organization
GO:0042470 IDA melanosome
GO:0043316 IEA cytotoxic T cell degranulation
GO:0043320 IEA natural killer cell degranulation
GO:0043473 IEA pigmentation
GO:0044267 TAS cellular protein metabolic process
GO:0045921 IMP positive regulation of exocytosis
GO:0048489 TAS synaptic vesicle transport
GO:0051875 IEA pigment granule localization
GO:0051904 IEA pigment granule transport
GO:0070062 IDA extracellular vesicular exosome
GO:0070382 IDA exocytic vesicle
GO:0071985 IMP multivesicular body sorting pathway
GO:1903307 IGI positive regulation of regulated secretory pathway
GO:1903435 IMP positive regulation of constitutive secretory pathway
GO:1990182 IMP exosomal secretion

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000040532 rab27a RAB27A, member RAS oncogene family protein_coding Danio_rerio
ENSMUSG00000032202 Rab27a RAB27A, member RAS oncogene family protein_coding Mus_musculus

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