C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: eukaryotic translation initiation factor 2B, subunit 3 gamma, 58kDa
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000360403 EIF2B3-001 ENSG00000070785 9606 - 1:44850778-44986610 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000360403
Transcript ID Adipose Adrenal Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000360403 7.132±0.00 9.806±0.00 7.276±2.80 18.680±0.00 8.681±0.00 8.811±5.77 4.514±4.11 7.636±0.00 3.801±3.14 11.669±9.96 7.486±4.61 6.007±1.58 20.190±1.44

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_000637 CIL_000637_0002 CGP 1:44819844-44986722

Gene Ontology

GO IDEvidence TypeGO Description
GO:0003743 IDA translation initiation factor activity
GO:0005085 IDA guanyl-nucleotide exchange factor activity
GO:0005515 IPI protein binding
GO:0005737 IDA cytoplasm
GO:0005829 TAS cytosol
GO:0005851 IDA eukaryotic translation initiation factor 2B complex
GO:0006412 TAS translation
GO:0006413 IDA translational initiation
GO:0006417 IEA regulation of translation
GO:0008135 IDA translation factor activity, nucleic acid binding
GO:0009058 IEA biosynthetic process
GO:0009408 ISS response to heat
GO:0009749 ISS response to glucose
GO:0010467 TAS gene expression
GO:0014003 IMP oligodendrocyte development
GO:0016779 IEA nucleotidyltransferase activity
GO:0032057 ISS negative regulation of translational initiation in response to stress
GO:0043434 ISS response to peptide hormone
GO:0043547 IDA positive regulation of GTPase activity
GO:0044267 TAS cellular protein metabolic process
GO:0051716 IDA cellular response to stimulus

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000106448 Eif2b3-001 protein_coding Mus_musculus 0 1762
ENSMUST00000106447 Eif2b3-201 protein_coding Mus_musculus 0 1489
ENSMUST00000070610 Eif2b3-002 protein_coding Mus_musculus 0 1489
ENSMUST00000155181 Eif2b3-003 processed_transcript Mus_musculus 0 514
ENSMUST00000135121 Eif2b3-004 processed_transcript Mus_musculus 0 422
ENSMUST00000129587 Eif2b3-006 processed_transcript Mus_musculus 0 279

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