C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: calcium/calmodulin-dependent protein kinase II alpha
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000070808 CAMK2A 9606 - 5:150219491-150290291 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000348628 CAMK2A-001 150219491-150290291 protein_coding
  ENST00000351010 CAMK2A-003 150221774-150245328 processed_transcript
  ENST00000398376 CAMK2A-002 150222691-150289629 protein_coding
  ENST00000507995 CAMK2A-006 150265142-150289787 processed_transcript
  ENST00000508662 CAMK2A-004 150238289-150289773 retained_intron
  ENST00000510347 CAMK2A-005 150257563-150290064 protein_coding
  ENST00000515758 CAMK2A-007 150253501-150265397 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000348628ENST00000351010ENST00000398376ENST00000508662
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000348628 N/A N/A 0.105±0.00 16.372±6.58 N/A N/A N/A 0.079±0.00 0.003±0.00 N/A N/A 0.068±0.05 0.072±0.06 0.060±0.00
ENST00000351010 N/A N/A 0.187±0.00 N/A 0.990±0.00 N/A 1.715±0.72 N/A 0.419±0.00 0.098±0.00 5.147±0.00 0.467±0.00 0.343±0.00 0.308±0.00
ENST00000398376 0.056±0.00 N/A 0.171±0.00 89.655±59.36 N/A 0.500±0.00 N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000508662 0.057±0.00 0.287±0.00 N/A N/A N/A N/A N/A N/A 0.143±0.13 N/A N/A N/A N/A 0.076±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00091Q CIL_00091Q_0001 VISTA 5:150006686-150608670

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000082 ISS G1/S transition of mitotic cell cycle
GO:0002931 ISS response to ischemia
GO:0004672 IEA protein kinase activity
GO:0004674 ISS protein serine/threonine kinase activity
GO:0004683 IEA calmodulin-dependent protein kinase activity
GO:0004713 IEA protein tyrosine kinase activity
GO:0005515 IPI protein binding
GO:0005516 IPI:IEA calmodulin binding
GO:0005524 IEA ATP binding
GO:0005634 IDA nucleus
GO:0005654 TAS nucleoplasm
GO:0005739 ISS mitochondrion
GO:0005829 TAS cytosol
GO:0005886 TAS plasma membrane
GO:0006468 IDA:IEA protein phosphorylation
GO:0006816 ISS calcium ion transport
GO:0007268 TAS synaptic transmission
GO:0010666 ISS positive regulation of cardiac muscle cell apoptotic process
GO:0016301 IDA kinase activity
GO:0016772 IEA transferase activity, transferring phosphorus-containing groups
GO:0018105 ISS peptidyl-serine phosphorylation
GO:0019221 TAS cytokine-mediated signaling pathway
GO:0030054 IEA cell junction
GO:0030666 TAS endocytic vesicle membrane
GO:0035254 ISS glutamate receptor binding
GO:0042803 IPI protein homodimerization activity
GO:0045202 IEA synapse
GO:0046777 ISS protein autophosphorylation
GO:0046928 ISS regulation of neurotransmitter secretion
GO:0048168 ISS regulation of neuronal synaptic plasticity
GO:0051092 IMP positive regulation of NF-kappaB transcription factor activity
GO:0051928 ISS positive regulation of calcium ion transport
GO:0060333 TAS interferon-gamma-mediated signaling pathway
GO:1902108 ISS regulation of mitochondrial membrane permeability involved in apoptotic process

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000053617 camk2a calcium/calmodulin-dependent protein kinase (CaM kinase) II alpha protein_coding Danio_rerio
ENSMUSG00000024617 Camk2a calcium/calmodulin-dependent protein kinase II alpha protein_coding Mus_musculus

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