C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: calcium/calmodulin-dependent protein kinase II alpha
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000024617 Camk2a 10090 + 18:60925618-60988152 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000025519 Camk2a-002 60925632-60986407 protein_coding
  ENSMUST00000039904 Camk2a-007 60963600-60985697 protein_coding
  ENSMUST00000102888 Camk2a-001 60925618-60988152 protein_coding
  ENSMUST00000115295 Camk2a-004 60963554-60984863 protein_coding
  ENSMUST00000115297 Camk2a-006 60925725-60943396 protein_coding
  ENSMUST00000134496 Camk2a-003 60925632-60943378 retained_intron
  ENSMUST00000137805 Camk2a-005 60926949-60955639 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000025519ENSMUST00000039904ENSMUST00000102888ENSMUST00000115295
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000025519 N/A 0.175±0.03 N/A 2.809±1.60 N/A 0.519±0.13 N/A N/A 0.040±0.05 N/A N/A 0.313±0.07 N/A N/A
ENSMUST00000039904 0.255±0.07 0.382±0.19 0.118±0.00 N/A 2.892±2.59 N/A 3.958±0.68 0.215±0.02 0.073±0.00 1.006±0.46 N/A 0.512±0.29 0.135±0.08 N/A
ENSMUST00000102888 N/A N/A 0.145±0.00 51.507±68.50 N/A 0.449±0.19 N/A N/A 0.023±0.01 N/A 91.643±8.47 0.408±0.34 0.045±0.00 0.004±0.00
ENSMUST00000115295 N/A 0.534±0.00 N/A N/A N/A N/A N/A N/A 0.049±0.00 N/A 94.207±0.00 N/A 0.100±0.02 0.073±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00091Q CIL_00091Q_0002 VISTA 18:60604549-61207221

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000082 IMP G1/S transition of mitotic cell cycle
GO:0002931 IMP response to ischemia
GO:0004674 IMP protein serine/threonine kinase activity
GO:0004683 IEA calmodulin-dependent protein kinase activity
GO:0005515 IPI protein binding
GO:0005516 IEA calmodulin binding
GO:0005524 IEA ATP binding
GO:0005634 IEA nucleus
GO:0005739 IMP mitochondrion
GO:0005886 IEA plasma membrane
GO:0005954 TAS calcium- and calmodulin-dependent protein kinase complex
GO:0006816 IMP calcium ion transport
GO:0010666 IMP positive regulation of cardiac muscle cell apoptotic process
GO:0016301 IEA kinase activity
GO:0018105 IMP peptidyl-serine phosphorylation
GO:0030054 IEA cell junction
GO:0035254 IPI glutamate receptor binding
GO:0042803 IEA protein homodimerization activity
GO:0045202 IEA synapse
GO:0046777 IMP protein autophosphorylation
GO:0046928 IMP regulation of neurotransmitter secretion
GO:0048168 IMP regulation of neuronal synaptic plasticity
GO:0051092 IEA positive regulation of NF-kappaB transcription factor activity
GO:0051928 IMP positive regulation of calcium ion transport
GO:1902108 IMP regulation of mitochondrial membrane permeability involved in apoptotic process

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000053617 camk2a calcium/calmodulin-dependent protein kinase (CaM kinase) II alpha protein_coding Danio_rerio
ENSG00000070808 CAMK2A calcium/calmodulin-dependent protein kinase II alpha protein_coding Homo_sapiens

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