C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: Fc fragment of IgG, low affinity IIb, receptor (CD32)
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000072694 FCGR2B 9606 + 1:161581311-161678654 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000236937 FCGR2B-005 161663147-161678022 protein_coding
  ENST00000358671 FCGR2B-002 161663161-161678654 protein_coding
  ENST00000367960 FCGR2B-201 161581311-161678650 protein_coding
  ENST00000367961 FCGR2B-001 161663161-161678032 protein_coding
  ENST00000403078 FCGR2B-202 161581311-161678650 protein_coding
  ENST00000428605 FCGR2B-203 161663224-161677569 protein_coding
  ENST00000480308 FCGR2B-003 161663192-161678053 retained_intron
  ENST00000485778 FCGR2B-004 161663199-161674116 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdrenalBladderBreastColonHeartKidneyLiverMuscleOvaryPlacentaTestisENST00000236937ENST00000358671ENST00000403078ENST00000480308
Transcript ID Adrenal Bladder Breast Colon Heart Kidney Liver Muscle Ovary Placenta Testis
ENST00000236937 N/A N/A 5.325±0.00 1.062±0.00 4.608±0.00 7.749±0.00 7.822±1.92 0.972±0.00 N/A 122.029±49.19 2.533±0.00
ENST00000358671 2.696±0.00 N/A 1.475±0.00 N/A 1.352±0.00 2.174±0.00 1.581±0.00 N/A N/A N/A 1.651±0.00
ENST00000403078 N/A N/A N/A N/A N/A N/A N/A 0.491±0.00 1.526±0.00 26.928±9.21 N/A
ENST00000480308 2.154±0.00 0.303±0.00 N/A 1.168±0.00 N/A N/A N/A N/A 0.661±0.00 N/A 0.360±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0005I7 CIL_0005I7_0001 CGP 1:161541759-161678654
CIL_0005I8 CIL_0005I8_0001 CGP 1:161581311-161678654

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005515 IPI:IEA protein binding
GO:0005886 TAS plasma membrane
GO:0006955 TAS immune response
GO:0007165 TAS signal transduction
GO:0016021 IEA integral component of membrane
GO:0016032 IEA viral process
GO:0019864 IEA IgG binding
GO:0050776 TAS regulation of immune response

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSMUSG00000026656 Fcgr2b Fc receptor, IgG, low affinity IIb protein_coding Mus_musculus
ENSMUSG00000059498 Fcgr3 Fc receptor, IgG, low affinity III protein_coding Mus_musculus

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