C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: Fc receptor, IgG, low affinity III
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000059498 Fcgr3 10090 - 1:171051174-171064935 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000164044 Fcgr3-001 171051175-171059403 protein_coding
  ENSMUST00000164179 Fcgr3-004 171057828-171064935 protein_coding
  ENSMUST00000168817 Fcgr3-003 171051174-171058054 retained_intron
  ENSMUST00000169017 Fcgr3-002 171051195-171059403 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000164044ENSMUST00000164179ENSMUST00000168817ENSMUST00000169017
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000164044 13.509±2.08 4.432±0.75 10.720±0.13 1.432±0.59 17.401±7.56 4.620±0.59 3.476±0.27 1.811±0.33 9.302±8.12 10.275±0.96 1.167±0.32 6.062±2.82 8.025±9.62 10.807±8.57
ENSMUST00000164179 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 14.178±13.14
ENSMUST00000168817 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 6.206±0.70 0.248±0.00
ENSMUST00000169017 4.737±1.18 1.071±0.39 2.298±0.25 0.695±0.00 4.639±0.61 1.684±0.77 1.441±0.22 0.968±0.35 1.771±1.25 3.436±0.67 0.464±0.00 2.356±1.32 2.261±1.23 4.348±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0005I7 CIL_0005I7_0002 CGP 1:171018920-171064935

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001788 IMP antibody-dependent cellular cytotoxicity
GO:0001798 IMP positive regulation of type IIa hypersensitivity
GO:0001805 IMP positive regulation of type III hypersensitivity
GO:0001812 IDA positive regulation of type I hypersensitivity
GO:0001820 IDA serotonin secretion
GO:0006910 IMP phagocytosis, recognition
GO:0006911 IMP phagocytosis, engulfment
GO:0007166 IMP cell surface receptor signaling pathway
GO:0019770 IMP IgG receptor activity
GO:0019864 IMP IgG binding
GO:0030593 IMP neutrophil chemotaxis
GO:0038094 IMP Fc-gamma receptor signaling pathway
GO:0042535 IMP positive regulation of tumor necrosis factor biosynthetic process
GO:0042590 IMP antigen processing and presentation of exogenous peptide antigen via MHC class I
GO:0045576 IDA mast cell activation
GO:0050766 IMP positive regulation of phagocytosis
GO:0050776 IMP regulation of immune response

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSG00000072694 FCGR2B Fc fragment of IgG, low affinity IIb, receptor (CD32) protein_coding Homo_sapiens
ENSG00000143226 FCGR2A Fc fragment of IgG, low affinity IIa, receptor (CD32) protein_coding Homo_sapiens
ENSG00000244682 FCGR2C Fc fragment of IgG, low affinity IIc, receptor for (CD32) (gene/pseudogene) polymorphic_pseudogene Homo_sapiens

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