C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: F-box and WD repeat domain containing 11
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000072803 FBXW11 9606 - 5:171861549-172006873 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000265094 FBXW11-002 171861552-172006640 protein_coding
  ENST00000296933 FBXW11-001 171861549-172006873 protein_coding
  ENST00000393802 FBXW11-003 171863621-172006650 protein_coding
  ENST00000517395 FBXW11-007 171899947-172006548 protein_coding
  ENST00000518106 FBXW11-010 171867778-171868662 processed_transcript
  ENST00000518752 FBXW11-008 171910672-171977756 protein_coding
  ENST00000519693 FBXW11-005 171899933-172006659 nonsense_mediated_decay
  ENST00000520376 FBXW11-006 171910631-172006649 nonsense_mediated_decay
  ENST00000522376 FBXW11-012 171867835-171876291 processed_transcript
  ENST00000522507 FBXW11-011 171910734-172006569 processed_transcript
  ENST00000522891 FBXW11-009 171876402-171908859 processed_transcript
  ENST00000523843 FBXW11-004 171863927-172006649 nonsense_mediated_decay

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000265094ENST00000296933ENST00000393802ENST00000522891ENST00000523843
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000265094 6.591±0.00 N/A N/A 11.067±9.39 7.686±0.00 10.883±0.00 9.547±0.00 5.776±4.17 2.259±0.00 11.856±0.00 2.798±0.00 7.350±0.00 3.672±0.00 3.138±0.47
ENST00000296933 3.733±0.00 1.401±0.00 1.477±0.00 4.790±3.02 1.763±1.26 0.742±0.00 2.416±1.75 1.051±0.32 1.695±0.86 2.886±0.29 4.831±4.38 4.365±3.52 1.217±0.12 5.083±0.18
ENST00000393802 N/A N/A 1.144±0.00 3.975±0.00 1.663±0.00 2.524±0.00 N/A N/A 3.973±0.00 N/A N/A N/A N/A N/A
ENST00000522891 N/A N/A 3.578±0.00 N/A N/A N/A N/A N/A N/A 4.333±0.00 2.233±0.00 N/A N/A N/A
ENST00000523843 N/A N/A 1.112±0.00 2.493±0.00 N/A N/A 2.922±0.00 N/A 2.135±0.00 4.001±0.00 2.293±0.00 3.300±0.00 N/A N/A

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000086 TAS G2/M transition of mitotic cell cycle
GO:0000151 NAS ubiquitin ligase complex
GO:0000209 IDA protein polyubiquitination
GO:0000278 TAS mitotic cell cycle
GO:0004842 NAS ubiquitin-protein transferase activity
GO:0005515 IPI:IEA protein binding
GO:0005634 ISS nucleus
GO:0005737 IEA cytoplasm
GO:0005813 IDA centrosome
GO:0005829 ISS cytosol
GO:0006470 ISS protein dephosphorylation
GO:0016055 IEA Wnt signaling pathway
GO:0016567 NAS protein ubiquitination
GO:0019005 IDA SCF ubiquitin ligase complex
GO:0031146 IDA SCF-dependent proteasomal ubiquitin-dependent protein catabolic process
GO:0031648 IMP protein destabilization
GO:0042347 IEA negative regulation of NF-kappaB import into nucleus
GO:0042753 ISS positive regulation of circadian rhythm
GO:0043161 IDA proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0045862 IMP positive regulation of proteolysis
GO:0045892 IMP negative regulation of transcription, DNA-templated
GO:0045893 ISS positive regulation of transcription, DNA-templated
GO:0046983 IEA protein dimerization activity
GO:0048511 IEA rhythmic process

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000017230 fbxw11b F-box and WD-40 domain protein 11b protein_coding Danio_rerio
ENSDARG00000028543 fbxw11a F-box and WD-40 domain protein 11a protein_coding Danio_rerio
ENSMUSG00000020271 Fbxw11 F-box and WD-40 domain protein 11 protein_coding Mus_musculus

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