C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: F-box and WD repeat domain containing 11
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000265094 FBXW11-002 ENSG00000072803 9606 - 5:171861552-172006640 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000265094
Transcript ID Adipose Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000265094 6.591±0.00 11.067±9.39 7.686±0.00 10.883±0.00 9.547±0.00 5.776±4.17 2.259±0.00 11.856±0.00 2.798±0.00 7.350±0.00 3.672±0.00 3.138±0.47

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000086 TAS G2/M transition of mitotic cell cycle
GO:0000151 NAS ubiquitin ligase complex
GO:0000209 IDA protein polyubiquitination
GO:0000278 TAS mitotic cell cycle
GO:0004842 NAS ubiquitin-protein transferase activity
GO:0005515 IPI:IEA protein binding
GO:0005634 ISS nucleus
GO:0005737 IEA cytoplasm
GO:0005813 IDA centrosome
GO:0005829 ISS cytosol
GO:0006470 ISS protein dephosphorylation
GO:0016055 IEA Wnt signaling pathway
GO:0016567 NAS protein ubiquitination
GO:0019005 IDA SCF ubiquitin ligase complex
GO:0031146 IDA SCF-dependent proteasomal ubiquitin-dependent protein catabolic process
GO:0031648 IMP protein destabilization
GO:0042347 IEA negative regulation of NF-kappaB import into nucleus
GO:0042753 ISS positive regulation of circadian rhythm
GO:0043161 IDA proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0045862 IMP positive regulation of proteolysis
GO:0045892 IMP negative regulation of transcription, DNA-templated
GO:0045893 ISS positive regulation of transcription, DNA-templated
GO:0046983 IEA protein dimerization activity
GO:0048511 IEA rhythmic process

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000093205 Fbxw11-002 protein_coding Mus_musculus 0 2525
ENSMUST00000076383 Fbxw11-201 protein_coding Mus_musculus 0 2218
ENSMUST00000109366 Fbxw11-001 protein_coding Mus_musculus 0 2218
ENSMUST00000143290 Fbxw11-003 nonsense_mediated_decay Mus_musculus 0 682
ENSMUST00000137898 Fbxw11-004 processed_transcript Mus_musculus 0 213

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