C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: F-box and WD-40 domain protein 11
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000020271 Fbxw11 10090 + 11:32642724-32746816 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000076383 Fbxw11-201 32642875-32746816 protein_coding
  ENSMUST00000093205 Fbxw11-002 32642866-32746789 protein_coding
  ENSMUST00000109366 Fbxw11-001 32642724-32746569 protein_coding
  ENSMUST00000137898 Fbxw11-004 32642784-32652904 processed_transcript
  ENSMUST00000143290 Fbxw11-003 32642904-32720574 nonsense_mediated_decay

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000076383ENSMUST00000093205ENSMUST00000109366
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000076383 N/A 13.709±4.94 2.676±0.00 N/A 8.442±1.23 14.482±5.23 1.494±0.00 8.178±0.00 3.353±2.66 12.986±0.00 1.534±0.05 11.310±5.41 3.700±0.00 0.927±0.00
ENSMUST00000093205 6.127±2.57 9.156±1.37 8.156±1.43 15.252±5.52 9.913±5.02 5.189±0.09 3.232±0.93 10.183±1.45 3.891±1.65 8.226±2.07 3.319±0.87 10.412±4.50 11.173±2.91 1.981±1.21
ENSMUST00000109366 16.971±5.81 30.431±4.51 9.862±0.30 13.228±8.34 23.149±9.66 9.112±2.85 5.361±3.20 16.804±5.44 5.623±2.34 16.659±4.13 5.262±1.27 15.346±5.27 7.314±3.17 3.025±0.49

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000209 IDA protein polyubiquitination
GO:0004842 IDA ubiquitin-protein transferase activity
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005737 IDA cytoplasm
GO:0005813 IEA centrosome
GO:0005829 IDA cytosol
GO:0006470 IDA protein dephosphorylation
GO:0007049 IEA cell cycle
GO:0016055 IEA Wnt signaling pathway
GO:0019005 IDA SCF ubiquitin ligase complex
GO:0031146 IMP SCF-dependent proteasomal ubiquitin-dependent protein catabolic process
GO:0031648 ISS protein destabilization
GO:0042347 IMP negative regulation of NF-kappaB import into nucleus
GO:0042752 ISS regulation of circadian rhythm
GO:0042753 IMP positive regulation of circadian rhythm
GO:0043161 ISS proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0045862 ISS positive regulation of proteolysis
GO:0045892 IEA negative regulation of transcription, DNA-templated
GO:0045893 IMP positive regulation of transcription, DNA-templated
GO:0046983 IEA protein dimerization activity
GO:0048511 IEA rhythmic process

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000017230 fbxw11b F-box and WD-40 domain protein 11b protein_coding Danio_rerio
ENSDARG00000028543 fbxw11a F-box and WD-40 domain protein 11a protein_coding Danio_rerio
ENSG00000072803 FBXW11 F-box and WD repeat domain containing 11 protein_coding Homo_sapiens

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