C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: ADAM metallopeptidase domain 11
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000073670 ADAM11 9606 + 17:44759031-44781846 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000200557 ADAM11-001 44759031-44781846 protein_coding
  ENST00000355638 ADAM11-002 44759179-44781647 nonsense_mediated_decay
  ENST00000535346 ADAM11-004 44759325-44779875 protein_coding
  ENST00000587773 ADAM11-005 44769986-44780610 nonsense_mediated_decay
  ENST00000588363 ADAM11-006 44775558-44777802 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000200557ENST00000355638ENST00000535346ENST00000587773ENST00000588363
Transcript ID Adipose Adrenal Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000200557 0.067±0.00 N/A 4.185±1.78 N/A 0.652±0.00 0.622±0.35 0.175±0.00 N/A 0.164±0.00 N/A 0.382±0.00 0.109±0.00 0.488±0.00
ENST00000355638 N/A N/A N/A N/A 0.139±0.00 N/A N/A N/A N/A N/A 0.147±0.00 0.079±0.03 0.362±0.19
ENST00000535346 N/A N/A N/A N/A N/A 1.308±0.00 N/A 0.030±0.02 N/A N/A N/A N/A 0.357±0.00
ENST00000587773 N/A 0.198±0.00 2.927±0.00 0.129±0.00 N/A 0.415±0.25 N/A 0.104±0.06 N/A 0.058±0.00 0.066±0.00 0.028±0.00 0.846±0.66
ENST00000588363 N/A N/A N/A N/A 0.921±0.00 N/A 0.283±0.00 0.354±0.00 N/A N/A N/A 0.116±0.00 1.760±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0007ST CIL_0007ST_0001 VISTA 17:44247434-44848646
CIL_0003CR CIL_0003CR_0001 CGP 17:44759031-44830816

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004222 IEA metalloendopeptidase activity
GO:0005178 TAS integrin binding
GO:0005515 IEA protein binding
GO:0005886 TAS plasma membrane
GO:0006508 IEA proteolysis
GO:0007229 TAS integrin-mediated signaling pathway
GO:0008237 TAS metallopeptidase activity
GO:0008270 IEA zinc ion binding
GO:0016021 IEA integral component of membrane
GO:0031012 ISS extracellular matrix

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000079204 adam11 a disintegrin and metalloproteinase domain 11 protein_coding Danio_rerio
ENSMUSG00000020926 Adam11 a disintegrin and metallopeptidase domain 11 protein_coding Mus_musculus

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