C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: ATP-binding cassette, sub-family B (MDR/TAP), member 11
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000073734 ABCB11 9606 - 2:168922938-169031322 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000263817 ABCB11-001 168922938-169031322 protein_coding
  ENST00000439188 ABCB11-003 168923383-168972032 nonsense_mediated_decay
  ENST00000478354 ABCB11-004 168969523-168970591 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdrenalBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000263817ENST00000439188ENST00000478354
Transcript ID Adrenal Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000263817 0.024±0.00 0.022±0.00 0.061±0.05 0.011±0.00 0.018±0.00 10.568±0.00 0.009±0.00 N/A N/A 0.037±0.00 0.016±0.00 N/A
ENST00000439188 0.082±0.00 0.011±0.00 N/A 0.261±0.25 0.011±0.00 N/A N/A 0.120±0.00 0.015±0.00 0.021±0.00 N/A 1.425±0.00
ENST00000478354 N/A N/A N/A N/A 0.028±0.00 N/A N/A N/A N/A N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008HC CIL_0008HC_0001 VISTA 2:168815051-169417863
CIL_0006HX CIL_0006HX_0001 CGP 2:168901240-169031322
CIL_0006HZ CIL_0006HZ_0001 CGP 2:168922938-169096167

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005215 TAS transporter activity
GO:0005524 IEA ATP binding
GO:0005886 TAS plasma membrane
GO:0005887 TAS integral component of plasma membrane
GO:0006200 IEA ATP catabolic process
GO:0006699 TAS bile acid biosynthetic process
GO:0006810 TAS:IEA transport
GO:0008206 TAS bile acid metabolic process
GO:0008554 TAS sodium-exporting ATPase activity, phosphorylative mechanism
GO:0015126 IBA canalicular bile acid transmembrane transporter activity
GO:0015432 TAS bile acid-exporting ATPase activity
GO:0015721 TAS bile acid and bile salt transport
GO:0015722 IBA canalicular bile acid transport
GO:0016020 TAS membrane
GO:0016021 IBA:IEA integral component of membrane
GO:0016887 IEA ATPase activity
GO:0035725 TAS sodium ion transmembrane transport
GO:0042626 IBA:IEA ATPase activity, coupled to transmembrane movement of substances
GO:0044281 TAS small molecule metabolic process
GO:0045177 IEA apical part of cell
GO:0046581 IEA intercellular canaliculus
GO:0055085 IBA:IEA transmembrane transport
GO:0070062 IDA extracellular vesicular exosome

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000070078 abcb11b ATP-binding cassette, sub-family B (MDR/TAP), member 11b protein_coding Danio_rerio
ENSMUSG00000027048 Abcb11 ATP-binding cassette, sub-family B (MDR/TAP), member 11 protein_coding Mus_musculus

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