C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: TXK tyrosine kinase
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000264316 TXK-001 ENSG00000074966 9606 - 4:48066393-48134256 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdrenalBrainKidneyLiverLungPlacentaTestisENST00000264316
Transcript ID Adrenal Brain Kidney Liver Lung Placenta Testis
ENST00000264316 0.401±0.00 0.013±0.00 0.412±0.00 0.095±0.01 0.284±0.00 0.236±0.00 0.304±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008RD CIL_0008RD_0001 VISTA 4:47524449-48126035
CIL_0001MY CIL_0001MY_0001 CGP 4:48066393-48269864

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001012 IDA RNA polymerase II regulatory region DNA binding
GO:0001816 ISS cytokine production
GO:0001865 IEA NK T cell differentiation
GO:0002250 ISS adaptive immune response
GO:0004672 IEA protein kinase activity
GO:0004713 IEA protein tyrosine kinase activity
GO:0004715 IEA non-membrane spanning protein tyrosine kinase activity
GO:0005515 IPI:IEA protein binding
GO:0005524 IEA ATP binding
GO:0005634 IDA nucleus
GO:0005737 IDA cytoplasm
GO:0005886 IEA plasma membrane
GO:0006351 IEA transcription, DNA-templated
GO:0006357 IDA regulation of transcription from RNA polymerase II promoter
GO:0006468 IEA:TAS protein phosphorylation
GO:0007202 ISS activation of phospholipase C activity
GO:0016772 IEA transferase activity, transferring phosphorus-containing groups
GO:0018108 IEA peptidyl-tyrosine phosphorylation
GO:0032609 IEA interferon-gamma production
GO:0032633 IEA interleukin-4 production
GO:0032729 IDA positive regulation of interferon-gamma production
GO:0046777 IDA protein autophosphorylation
GO:0050852 ISS T cell receptor signaling pathway
GO:0060335 IDA positive regulation of interferon-gamma-mediated signaling pathway

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000113604 Txk-201 protein_coding Mus_musculus 0 1363
ENSMUST00000169534 Txk-202 protein_coding Mus_musculus 0 1327

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