C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: diacylglycerol kinase, delta 130kDa
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000077044 DGKD 9606 + 2:233354507-233472104 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000264057 DGKD-001 233354507-233472100 protein_coding
  ENST00000409813 DGKD-010 233388154-233472096 protein_coding
  ENST00000427930 DGKD-011 233354508-233435894 protein_coding
  ENST00000430834 DGKD-003 233438313-233472104 nonsense_mediated_decay
  ENST00000442524 DGKD-014 233354572-233392399 protein_coding
  ENST00000447484 DGKD-004 233385945-233434899 protein_coding
  ENST00000465569 DGKD-007 233448030-233449172 retained_intron
  ENST00000471764 DGKD-008 233458239-233459867 retained_intron
  ENST00000472732 DGKD-012 233408891-233435924 processed_transcript
  ENST00000474488 DGKD-002 233434467-233442591 retained_intron
  ENST00000480535 DGKD-006 233447701-233449155 processed_transcript
  ENST00000489613 DGKD-013 233386054-233388985 retained_intron
  ENST00000490764 DGKD-005 233419241-233457817 retained_intron
  ENST00000495901 DGKD-009 233463814-233467150 retained_intron
  ENST00000622717 DGKD-201 233388154-233472096 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000264057ENST00000409813ENST00000430834ENST00000447484ENST00000474488ENST00000490764ENST00000495901ENST00000622717
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000264057 0.951±0.00 1.826±0.00 0.256±0.00 0.777±0.06 0.964±0.52 1.793±0.47 0.697±0.47 0.766±0.49 0.796±0.35 1.677±0.00 2.408±0.00 3.488±0.62 5.365±2.11 7.399±2.32
ENST00000409813 N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.627±0.00 0.937±0.00 1.198±0.00 N/A N/A
ENST00000430834 N/A N/A N/A N/A 0.542±0.00 0.625±0.00 N/A 0.477±0.00 N/A 5.016±0.00 4.215±0.99 2.966±0.55 2.403±0.00 5.405±0.00
ENST00000447484 N/A N/A N/A N/A N/A N/A N/A 1.991±0.00 N/A N/A N/A N/A N/A N/A
ENST00000474488 N/A N/A N/A N/A N/A N/A N/A 0.713±0.00 N/A N/A N/A N/A N/A N/A
ENST00000490764 N/A N/A N/A 0.977±0.43 N/A N/A 0.508±0.00 N/A N/A N/A N/A 0.993±0.00 N/A N/A
ENST00000495901 N/A N/A N/A N/A N/A N/A N/A 1.798±0.00 N/A N/A N/A N/A N/A N/A
ENST00000622717 N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.634±0.00 N/A 1.242±0.00 N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0003RA CIL_0003RA_0001 CGP 2:233307816-233472104
CIL_0003R9 CIL_0003R9_0001 CGP 2:233354507-233566782

Gene Ontology
GO IDEvidence TypeGO Description
GO:0003951 IEA NAD+ kinase activity
GO:0004143 IDA:IEA diacylglycerol kinase activity
GO:0005515 IPI:IEA protein binding
GO:0005524 IEA ATP binding
GO:0005737 IDA cytoplasm
GO:0005886 IDA plasma membrane
GO:0006897 IEA endocytosis
GO:0007165 TAS signal transduction
GO:0007173 NAS epidermal growth factor receptor signaling pathway
GO:0007205 NAS:IEA protein kinase C-activating G-protein coupled receptor signaling pathway
GO:0007275 NAS multicellular organismal development
GO:0007596 TAS blood coagulation
GO:0010033 IDA response to organic substance
GO:0015031 IEA protein transport
GO:0016023 IDA cytoplasmic membrane-bounded vesicle
GO:0016049 NAS cell growth
GO:0016310 IEA phosphorylation
GO:0019932 NAS second-messenger-mediated signaling
GO:0019992 NAS diacylglycerol binding
GO:0030168 TAS platelet activation
GO:0035556 IEA intracellular signal transduction
GO:0042803 IDA protein homodimerization activity
GO:0046339 IC diacylglycerol metabolic process
GO:0046872 IEA metal ion binding
GO:0046982 IDA protein heterodimerization activity
GO:0051260 IDA protein homooligomerization

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSMUSG00000070738 Dgkd diacylglycerol kinase, delta protein_coding Mus_musculus

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